[HTML][HTML] Oligonucleotide aptamers: Recent advances in their screening, molecular conformation and therapeutic applications
X Xiao, H Li, L Zhao, Y Zhang, Z Liu - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Aptamers are single stranded oligonucleotides with specific recognition and binding ability
to target molecules, which can be obtained by Systematic Evolution of Ligands by …
to target molecules, which can be obtained by Systematic Evolution of Ligands by …
Thermostability, tunability, and tenacity of RNA as rubbery anionic polymeric materials in nanotechnology and nanomedicine—specific cancer targeting with …
RNA nanotechnology is the bottom-up self-assembly of nanometer-scale architectures,
resembling LEGOs, composed mainly of RNA. The ideal building material should be (1) …
resembling LEGOs, composed mainly of RNA. The ideal building material should be (1) …
Incorporating chemical modification constraints into a dynamic programming algorithm for prediction of RNA secondary structure
DH Mathews, MD Disney, JL Childs… - Proceedings of the …, 2004 - National Acad Sciences
A dynamic programming algorithm for prediction of RNA secondary structure has been
revised to accommodate folding constraints determined by chemical modification and to …
revised to accommodate folding constraints determined by chemical modification and to …
Thermodynamically Stable RNA Three-Way Junction for Constructing Multifunctional Nanoparticles for Delivery of Therapeutics 1
RNA nanoparticles have applications in the treatment of cancers and viral infection;
however, the instability of RNA nanoparticles has hindered their applications for therapeutic …
however, the instability of RNA nanoparticles has hindered their applications for therapeutic …
Using an RNA secondary structure partition function to determine confidence in base pairs predicted by free energy minimization
DH Mathews - Rna, 2004 - rnajournal.cshlp.org
A partition function calculation for RNA secondary structure is presented that uses a current
set of nearest neighbor parameters for conformational free energy at 37° C, including …
set of nearest neighbor parameters for conformational free energy at 37° C, including …
RNA STRAND: the RNA secondary structure and statistical analysis database
Background The ability to access, search and analyse secondary structures of a large set of
known RNA molecules is very important for deriving improved RNA energy models, for …
known RNA molecules is very important for deriving improved RNA energy models, for …
Improved RNA secondary structure prediction by maximizing expected pair accuracy
ZJ Lu, JW Gloor, DH Mathews - Rna, 2009 - rnajournal.cshlp.org
Free energy minimization has been the most popular method for RNA secondary structure
prediction for decades. It is based on a set of empirical free energy change parameters …
prediction for decades. It is based on a set of empirical free energy change parameters …
ProbKnot: fast prediction of RNA secondary structure including pseudoknots
S Bellaousov, DH Mathews - Rna, 2010 - rnajournal.cshlp.org
It is a significant challenge to predict RNA secondary structures including pseudoknots.
Here, a new algorithm capable of predicting pseudoknots of any topology, ProbKnot, is …
Here, a new algorithm capable of predicting pseudoknots of any topology, ProbKnot, is …
Bridging the gap between in vitro and in vivo RNA folding
Deciphering the folding pathways and predicting the structures of complex three-
dimensional biomolecules is central to elucidating biological function. RNA is single …
dimensional biomolecules is central to elucidating biological function. RNA is single …
Evaluation of the suitability of free-energy minimization using nearest-neighbor energy parameters for RNA secondary structure prediction
KJ Doshi, JJ Cannone, CW Cobaugh, RR Gutell - BMC bioinformatics, 2004 - Springer
Background A detailed understanding of an RNA's correct secondary and tertiary structure is
crucial to understanding its function and mechanism in the cell. Free energy minimization …
crucial to understanding its function and mechanism in the cell. Free energy minimization …