High-energy metal–organic frameworks (HE-MOFs): Synthesis, structure and energetic performance

S Zhang, Q Yang, X Liu, X Qu, Q Wei, G Xie… - Coordination Chemistry …, 2016 - Elsevier
Recent progress in high-energy metal–organic frameworks (HE-MOFs), not only a
burgeoning branch of growing interest in energetic materials but also a particular class of …

Novel 1, 2, 4-oxadiazole derivatives in drug discovery

K Biernacki, M Daśko, O Ciupak, K Kubiński, J Rachon… - Pharmaceuticals, 2020 - mdpi.com
Five-membered 1, 2, 4-oxadiazole heterocyclic ring has received considerable attention
because of its unique bioisosteric properties and an unusually wide spectrum of biological …

Nitrotetrazolate-2N-oxides and the Strategy of N-Oxide Introduction

M Göbel, K Karaghiosoff, TM Klapötke… - Journal of the …, 2010 - ACS Publications
The first anionic tetrazole-2 N-oxide has been prepared by mild aqueous oxidation of easily
prepared 5-nitrotetrazole with commercially available oxone in high yields. The result of …

Synthetic chalcones, flavanones, and flavones as antitumoral agents: Biological evaluation and structure–activity relationships

M Cabrera, M Simoens, G Falchi, ML Lavaggi… - Bioorganic & Medicinal …, 2007 - Elsevier
A series of synthetic chalcones, flavanones, and flavones has been synthesized and
evaluated for antitumor activity against the human kidney carcinoma cells TK-10, human …

Polysubstituted pyrazoles, part 5. Synthesis of new 1-(4-chlorophenyl)-4-hydroxy-1H-pyrazole-3-carboxylic acid hydrazide analogs and some derived ring systems. A …

SAF Rostom, MA Shalaby, MA El-Demellawy - European Journal of …, 2003 - Elsevier
A novel series of 1-(4-chlorophenyl)-4-hydroxy-1H-pyrazole-3-carboxylic acid hydrazide
analogs and some derived 4-substituted-1, 2, 4-triazolin-3-thiones, 2-substituted-1, 3, 4 …

Design of anticancer prodrugs for reductive activation

Y Chen, L Hu - Medicinal research reviews, 2009 - Wiley Online Library
Anticancer prodrugs designed to target specifically tumor cells should increase therapeutic
effectiveness and decrease systemic side effects in the treatment of cancer. Over the last 20 …

Pharmacological properties of furoxans and benzofuroxans: recent developments

H Cerecetto, W Porcal - Mini reviews in medicinal chemistry, 2005 - benthamdirect.com
The chemistry of furoxans (1, 2, 5-oxadiazole-2-oxides) and benzofuroxans (benzo [1, 2-c] 1,
2, 5-oxadiazole-1-oxides) is very well known. These systems are widely used in organic …

Recent progress in the development of synthetic hybrids of natural or unnatural bioactive compounds for medicinal chemistry

SB Tsogoeva - Mini reviews in medicinal chemistry, 2010 - ingentaconnect.com
The present mini-review highlights the recent developments on different classes of synthetic
hybrids of natural and/or unnatural bioactive compounds, the utilization of which is very …

Synthesis and biological activities of oxadiazole derivatives: a review

A Vaidya, S Jain, P Jain, P Jain, N Tiwari… - Mini Reviews in …, 2016 - ingentaconnect.com
Recently, there has been wide interest in compounds containing the oxadiazole scaffold
because of their unique chemical structure and their broad spectrum of biological properties …

Discovery of NO Donor-Aurovertin Hybrids as Dual Ferroptosis and Apoptosis Inducers for Treating Triple Negative Breast Cancer

LF Ma, LL Xu, LJ Yuan, X Yang, R Wu… - Journal of Medicinal …, 2024 - ACS Publications
Triple-negative breast cancer (TNBC) is a highly lethal malignancy, and its clinical
management encounters severe challenges due to its high metastatic propensity and the …