A Guide to the Metabolic Pathways and Function of Metabolites Observed in Human Brain 1H Magnetic Resonance Spectra

CD Rae - Neurochemical research, 2014 - Springer
The current knowledge of the normal biochemistry of compounds that give rise to
resonances in human brain proton magnetic resonance spectra measureable at readily …

The structural basis of inter-individual differences in human behaviour and cognition

R Kanai, G Rees - Nature Reviews Neuroscience, 2011 - nature.com
Inter-individual variability in perception, thought and action is frequently treated as a source
of'noise'in scientific investigations of the neural mechanisms that underlie these processes …

The reliability paradox: Why robust cognitive tasks do not produce reliable individual differences

C Hedge, G Powell, P Sumner - Behavior research methods, 2018 - Springer
Individual differences in cognitive paradigms are increasingly employed to relate cognition
to brain structure, chemistry, and function. However, such efforts are often unfruitful, even …

Intracortical GABAergic dysfunction in patients with fatigue and dysexecutive syndrome after COVID-19

V Versace, L Sebastianelli, D Ferrazzoli… - Clinical …, 2021 - Elsevier
Objective A high proportion of patients experience fatigue and impairment of cognitive
functions after coronavirus disease 2019 (COVID-19). Here we applied transcranial …

Altered motor cortex physiology and dysexecutive syndrome in patients with fatigue and cognitive difficulties after mild COVID‐19

P Ortelli, D Ferrazzoli, L Sebastianelli… - European journal of …, 2022 - Wiley Online Library
Background and purpose Fatigue and cognitive difficulties are reported as the most
frequently persistent symptoms in patients after mild SARS‐CoV‐2 infection. An extensive …

In vivo magnetic resonance spectroscopy of GABA: a methodological review

NAJ Puts, RAE Edden - Progress in nuclear magnetic resonance …, 2012 - Elsevier
Conclusion MRS has become established as a robust and powerful tool for the investigation
of the inhibitory neurotransmitter GABA. This is a significant success, given the significant …

Edited magnetic resonance spectroscopy detects an age-related decline in brain GABA levels

F Gao, RAE Edden, M Li, NAJ Puts, G Wang, C Liu… - Neuroimage, 2013 - Elsevier
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the brain.
Although measurements of GABA levels in vivo in the human brain using edited proton …

Relationship between physiological measures of excitability and levels of glutamate and GABA in the human motor cortex

CJ Stagg, S Bestmann… - The Journal of …, 2011 - Wiley Online Library
Non‐technical summary Inter‐individual differences in regional GABA as assessed by
magnetic resonance spectroscopy (MRS) relate to behavioural variation in humans …

Frontal gamma-aminobutyric acid concentrations are associated with cognitive performance in older adults

EC Porges, AJ Woods, RAE Edden, NAJ Puts… - Biological psychiatry …, 2017 - Elsevier
Background Gamma-aminobutyric acid (GABA), the brain's principal inhibitory
neurotransmitter, has been associated with perceptual and attentional functioning. Recent …

Reduced GABA concentration in attention-deficit/hyperactivity disorder

RAE Edden, D Crocetti, H Zhu, DL Gilbert… - Archives of general …, 2012 - jamanetwork.com
Context Attention-deficit/hyperactivity disorder (ADHD) is a developmental disorder
characterized by a deficit in behavioral inhibition. Recent evidence also suggests a deficit in …