Advanced optical tweezers on cell manipulation and analysis

S Hu, J Ye, Y Zhao, C Zhu - The European Physical Journal Plus, 2022 - Springer
Optical tweezers (OTs), which generate a variety of fascinating beam patterns, allow
biologists to uncover the natural secrets of human life at single-cell level. Due to its gentle …

Microfluidics-based approaches to the isolation of African trypanosomes

MP Barrett, JM Cooper, C Regnault, SH Holm… - Pathogens, 2017 - mdpi.com
African trypanosomes are responsible for significant levels of disease in both humans and
animals. The protozoan parasites are free-living flagellates, usually transmitted by arthropod …

Optical trapping reveals propulsion forces, power generation and motility efficiency of the unicellular parasites Trypanosoma brucei brucei

E Stellamanns, S Uppaluri, A Hochstetter… - Scientific reports, 2014 - nature.com
Unicellular parasites have developed sophisticated swimming mechanisms to survive in a
wide range of environments. Cell motility of African trypanosomes, parasites responsible for …

Evaluating viscoelastic properties and membrane electrical charges of red blood cells with optical tweezers and cationic quantum dots–applications to β-thalassemia …

CN Lima, DS Moura, YSS Silva, TH Souza… - Colloids and Surfaces B …, 2020 - Elsevier
Biomechanical and electrical properties are important to the performance and survival of red
blood cells (RBCs) in the microcirculation. This study proposed and explored methodologies …

Identification of positive chemotaxis in the protozoan pathogen Trypanosoma brucei

SF DeMarco, EA Saada, MA Lopez, KL Hill - Msphere, 2020 - Am Soc Microbiol
To complete its infectious cycle, the protozoan parasite Trypanosoma brucei must navigate
through diverse tissue environments in both its tsetse fly and mammalian hosts. This is …

Motility, force generation, and energy consumption of unicellular parasites

A Hochstetter, T Pfohl - Trends in parasitology, 2016 - cell.com
Motility is a key factor for pathogenicity of unicellular parasites, enabling them to infiltrate
and evade host cells, and perform several of their life-cycle events. State-of-the-art methods …

High-speed, three-dimensional imaging reveals chemotactic behaviour specific to human-infective Leishmania parasites

RC Findlay, M Osman, KA Spence, PM Kaye… - Elife, 2021 - elifesciences.org
Cellular motility is an ancient eukaryotic trait, ubiquitous across phyla with roles in predator
avoidance, resource access, and competition. Flagellar motility is seen in various parasitic …

Identification of positive chemotaxis in the protozoan pathogen Trypanosoma brucei

SF DeMarco, EA Saada, MA Lopez, KL Hill - bioRxiv, 2019 - biorxiv.org
To complete its infectious cycle, the protozoan parasite, Trypanosoma brucei, must navigate
through diverse tissue environments in both its tsetse fly and mammalian hosts. This is …

TrypanoFluidique: compartimentation, culture et analyse de la microfluidique de gouttes de Trypanosoma brucei

S Oldenburg - 2021 - theses.hal.science
Trypanosoma brucei are protozoan parasites infecting mammals in Sub-Saharan Africa
causing the disease known as Sleeping sickness. The parasites are transmitted between the …

[PDF][PDF] Hybrid Optical and Acoustic Trapping

G Brodie - 2014 - core.ac.uk
The need for non-invasive micromanipulation methods has become very important for many
aspects of cell biology, molecular studies and nanotechnology. The desire to have full and …