Progress and renewal in gustation: new insights into taste bud development
LA Barlow - Development, 2015 - journals.biologists.com
The sense of taste, or gustation, is mediated by taste buds, which are housed in specialized
taste papillae found in a stereotyped pattern on the surface of the tongue. Each bud …
taste papillae found in a stereotyped pattern on the surface of the tongue. Each bud …
Taste bud homeostasis in health, disease, and aging
The mammalian taste bud is an onion-shaped epithelial structure with 50–100 tightly packed
cells, including taste receptor cells, supporting cells, and basal cells. Taste receptor cells …
cells, including taste receptor cells, supporting cells, and basal cells. Taste receptor cells …
[HTML][HTML] Pleiotropic functions of embryonic sonic hedgehog expression link jaw and taste bud amplification with eye loss during cavefish evolution
Y Yamamoto, MS Byerly, WR Jackman… - Developmental biology, 2009 - Elsevier
This study addresses the role of sonic hedgehog (shh) in increasing oral–pharyngeal
constructive traits (jaws and taste buds) at the expense of eyes in the blind cavefish …
constructive traits (jaws and taste buds) at the expense of eyes in the blind cavefish …
Developing and regenerating a sense of taste
Taste is one of the fundamental senses, and it is essential for our ability to ingest nutritious
substances and to detect and avoid potentially toxic ones. Taste buds, which are clusters of …
substances and to detect and avoid potentially toxic ones. Taste buds, which are clusters of …
Anatomy and development of the human taste system
M Witt - Handbook of clinical neurology, 2019 - Elsevier
The sense of taste relies on well-defined neuroanatomical structures, namely, the taste buds
and afferent nerve fibers. Taste buds are clusters of 50–100 neuroepithelial cells located …
and afferent nerve fibers. Taste buds are clusters of 50–100 neuroepithelial cells located …
The sense of taste: Development, regeneration, and dysfunction
LA Barlow - WIREs mechanisms of disease, 2022 - Wiley Online Library
Gustation or the sense of taste is a primary sense, which functions as a gatekeeper for
substances that enter the body. Animals, including humans, ingest foods that contain …
substances that enter the body. Animals, including humans, ingest foods that contain …
Cell lineage and differentiation in taste buds
H Miura, Y Kusakabe, S Harada - Archives of histology and cytology, 2006 - jstage.jst.go.jp
Mammalian taste buds are maintained through continuous cell renewal so that taste bud
cells are constantly generated from progenitor cells throughout life. Taste bud cells are …
cells are constantly generated from progenitor cells throughout life. Taste bud cells are …
Developing a sense of taste
M Kapsimali, LA Barlow - Seminars in cell & developmental biology, 2013 - Elsevier
Taste buds are found in a distributed array on the tongue surface, and are innervated by
cranial nerves that convey taste information to the brain. For nearly a century, taste buds …
cranial nerves that convey taste information to the brain. For nearly a century, taste buds …
Induction of ectopic taste buds by SHH reveals the competency and plasticity of adult lingual epithelium
D Castillo, K Seidel, E Salcedo, C Ahn… - …, 2014 - journals.biologists.com
Taste buds are assemblies of elongated epithelial cells, which are innervated by gustatory
nerves that transmit taste information to the brain stem. Taste cells are continuously renewed …
nerves that transmit taste information to the brain stem. Taste cells are continuously renewed …
Transcriptome analyses of taste organoids reveal multiple pathways involved in taste cell generation
W Ren, E Aihara, W Lei, N Gheewala, H Uchiyama… - Scientific reports, 2017 - nature.com
Taste cells undergo constant turnover throughout life; however, the molecular mechanisms
governing taste cell generation are not well understood. Using RNA-Seq, we systematically …
governing taste cell generation are not well understood. Using RNA-Seq, we systematically …