Circadian regulation in aging: Implications for spaceflight and life on earth
Alterations in the circadian system are characteristic of aging on Earth. With the decline in
physiological processes due to aging, several health concerns including vision loss …
physiological processes due to aging, several health concerns including vision loss …
Sarcopenia: what is the origin of this aging-induced disorder?
T Gustafsson, B Ulfhake - Frontiers in genetics, 2021 - frontiersin.org
We here review the loss of muscle function and mass (sarcopenia) in the framework of
human healthspan and lifespan, and mechanisms involved in aging. The rapidly changing …
human healthspan and lifespan, and mechanisms involved in aging. The rapidly changing …
Identification and characterization of genomic predictors of sarcopenia and sarcopenic obesity using UK biobank data
EA Semenova, E Pranckevičienė, EA Bondareva… - Nutrients, 2023 - mdpi.com
The substantial decline in skeletal muscle mass, strength, and gait speed is a sign of severe
sarcopenia, which may partly depend on genetic risk factors. So far, hundreds of genome …
sarcopenia, which may partly depend on genetic risk factors. So far, hundreds of genome …
Anabolic resistance in the pathogenesis of sarcopenia in the elderly: role of nutrition and exercise in young and old people
C Tezze, M Sandri, P Tessari - Nutrients, 2023 - mdpi.com
The development of sarcopenia in the elderly is associated with many potential factors
and/or processes that impair the renovation and maintenance of skeletal muscle mass and …
and/or processes that impair the renovation and maintenance of skeletal muscle mass and …
Neuromuscular junction aging: a role for biomarkers and exercise
Age-related skeletal muscle degradation known as “sarcopenia” exerts considerable strain
on public health systems globally. While the pathogenesis of such atrophy is undoubtedly …
on public health systems globally. While the pathogenesis of such atrophy is undoubtedly …
Plasma neurofilament light levels associate with muscle mass and strength in middle‐aged and older adults: Findings from GenoFit
Background Efforts to enhance diagnostic measures for sarcopenia have led to an
increased focus on the screening utility of blood‐based biomarkers. In this regard …
increased focus on the screening utility of blood‐based biomarkers. In this regard …
Putting some muscle into sarcopenia—the pathogenesis, assessment and clinical impact of muscle loss in patients with inflammatory bowel disease
Background Sarcopenia, a loss of skeletal muscle mass or function, affects up to 50% of
patients with inflammatory bowel disease (IBD) and is associated with poor clinical …
patients with inflammatory bowel disease (IBD) and is associated with poor clinical …
Association between polygenetic risk scores related to sarcopenia risk and their interactions with regular exercise in a large cohort of Korean adults
S Park - Clinical Nutrition, 2021 - Elsevier
Background & aims Sarcopenia elevates metabolic disorders in the elderly, and genetic and
environmental factors influence the risk of sarcopenia. The purpose of the study was to …
environmental factors influence the risk of sarcopenia. The purpose of the study was to …
Plasma C-terminal agrin fragment as an early biomarker for sarcopenia: results from the GenoFit study
Barriers associated with direct muscle quantification have prevented a consistent
implementation of therapeutic measures for sarcopenia. Recently, the relevance of …
implementation of therapeutic measures for sarcopenia. Recently, the relevance of …
Walking pace, handgrip strength, age, APOE genotypes, and new-onset dementia: the UK Biobank prospective cohort study
P He, C Zhou, Z Ye, M Liu, Y Zhang, Q Wu… - Alzheimer's research & …, 2023 - Springer
Background The independent and additive associations of walking pace and grip strength
on dementia risk and the potential modifying effects of age, APOE phenotypes, and other …
on dementia risk and the potential modifying effects of age, APOE phenotypes, and other …