Mechanisms of resistance and current treatment options for glioblastoma multiforme (GBM)
Simple Summary Glioblastoma multiforme is one of the hardest-to-treat brain tumors, often
resistant to conventional treatments such as chemotherapy and radiation therapy. Despite …
resistant to conventional treatments such as chemotherapy and radiation therapy. Despite …
Role of glioblastoma stem cells in cancer therapeutic resistance: A perspective on antineoplastic agents from natural sources and chemical derivatives
ALV Alves, INF Gomes, AC Carloni, MN Rosa… - Stem Cell Research & …, 2021 - Springer
Glioblastoma (GBM) is the highest-grade form of glioma, as well as one of the most
aggressive types of cancer, exhibiting rapid cellular growth and highly invasive behavior …
aggressive types of cancer, exhibiting rapid cellular growth and highly invasive behavior …
Targeted liposomes for combined delivery of artesunate and temozolomide to resistant glioblastoma
M Ismail, W Yang, Y Li, T Chai, D Zhang, Q Du… - Biomaterials, 2022 - Elsevier
The effective treatment of glioblastoma (GBM) is a great challenge because of the blood-
brain barrier (BBB) and the growing resistance to single-agent therapeutics. Targeted …
brain barrier (BBB) and the growing resistance to single-agent therapeutics. Targeted …
Impact of PEGylated liposomal doxorubicin and carboplatin combination on glioblastoma
M Ghaferi, A Raza, M Koohi, W Zahra, A Akbarzadeh… - Pharmaceutics, 2022 - mdpi.com
Glioblastoma is an incurable cancer with a 5-year survival chance of less than 5%.
Chemotherapy is a therapeutic approach to treating the disease; however, due to the …
Chemotherapy is a therapeutic approach to treating the disease; however, due to the …
Recent advances in drug delivery systems for targeting brain tumors
Y Zhao, P Yue, Y Peng, Y Sun, X Chen, Z Zhao… - Drug delivery, 2023 - Taylor & Francis
Brain tumor accounts for about 1.6% of incidence and 2.5% of mortality of all tumors, and the
median survival for brain tumor patients is only about 20 months. The treatment for brain …
median survival for brain tumor patients is only about 20 months. The treatment for brain …
Benefits and limitations of nanomedicine treatment of brain cancers and age-dependent neurodegenerative disorders
ME Neganova, YR Aleksandrova… - Seminars in Cancer …, 2022 - Elsevier
The treatment of central nervous system (CNS) malignancies, including brain cancers, is
limited by a number of obstructions, including the blood-brain barrier (BBB), the …
limited by a number of obstructions, including the blood-brain barrier (BBB), the …
Polymeric nanoparticles for drug delivery in glioblastoma: State of the art and future perspectives
Glioblastoma (GBM) is an aggressive, fatal and malignant primary brain tumor. Despite the
current standard treatment for glioblastoma patients including neurosurgical resection …
current standard treatment for glioblastoma patients including neurosurgical resection …
Upconversion nanoparticle-based cell membrane-coated cRGD peptide bioorthogonally labeled nanoplatform for glioblastoma treatment
Glioblastoma is hard to be eradicated partly because of the obstructive blood–brain barrier
(BBB) and the dynamic autophagy activities of glioblastoma. Here, hydroxychloroquine …
(BBB) and the dynamic autophagy activities of glioblastoma. Here, hydroxychloroquine …
Role of nanomedicine-based therapeutics in the treatment of CNS disorders
Central nervous system disorders, especially neurodegenerative diseases, are a public
health priority and demand a strong scientific response. Various therapy procedures have …
health priority and demand a strong scientific response. Various therapy procedures have …
Targeting glioblastoma stem cells to overcome chemoresistance: an overview of current therapeutic strategies
Glioblastoma (GBM) is the most malignant primary brain tumor. The current standard
approach in GBM is surgery, followed by treatment with radiation and temozolomide (TMZ); …
approach in GBM is surgery, followed by treatment with radiation and temozolomide (TMZ); …