Adrenal glucocorticoids are major modulators of multiple functions, including energy
metabolism, stress responses, immunity, and cognition. The endogenous secretion of …

Light has profoundly influenced the evolution of life on earth. As widely appreciated, light
enables us to generate images of our environment. However, light—through intrinsically …

The effects of adrenal corticosteroids on subsequent adrenocorticotropin secretion are
complex. Acutely (within hours), glucocorticoids (GCs) directly inhibit further activity in the …

Data from rodent studies indicate that cumulative stress exposure may accelerate
senescence and offer a theory to explain differences in the rate of aging. Cumulative …

The pattern of endogenous insulin secretion over a 24-h period, which included three mixed
meals, was evaluated in 14 normal volunteers and 15 obese subjects. Insulin secretory rates …

ContextIn young adults, sleep affects the regulation of growth hormone (GH) and cortisol.
The relationship between decreased sleep quality in older adults and age-related changes …

The pronounced daily variation in the release of adrenal hormones has been at the heart of
the deciphering and understanding of the circadian timing system. Indeed, the first …

This study examined the effects of perceived stress and related individual characteristics,
mood states, and stressful daily events on salivary cortisol levels. Forty-one" high stress" and …

The aim of the present study was to evaluate the pattern of basal cortisol release in PTSD
and major depression using a chronobiological analysis. Plasma for cortisol determination …

Advances in the technologic armamentarium available to basic and clinical investigators
have enabled increasingly sophisticated studies of brain function in health and disease. This …