The therapeutic control of a solid tumour depends critically on the responses of the
individual cells that constitute the entire tumour mass. A particular cell's spatial location …

With the dawn of 3D printing technology, patient-specific implant designs are set to have a
paradigm shift. A topology optimization method in designing patient-specific craniofacial …

Restoring normal function and appearance after massive facial injuries with bone loss is an
important unsolved problem in surgery. An important limitation of the current methods is …

Insufficient oxygenation is a key obstacle in the design of clinically scalable tissue‐
engineered grafts. In this work, an oxygen‐generating composite material, termed OxySite …

The role of the microvascular network geometry in transport phenomena in solid tumors and
its interplay with the leakage and pressure drop across the vessels is qualitatively and …

Radiotherapy is a commonly used treatment for cancer and is usually given in varying
doses. At low radiation doses relatively few cells die as a direct response to radiation but …

Gliomas are highly invasive brain tumours characterised by poor prognosis and limited
response to therapy. There is an ongoing debate on the therapeutic potential of vaso …

Tumor oxygenation status is considered one of the important prognostic markers in cancer
since it strongly influences the response of cancer cells to various treatments; in particular, to …

The processes of wound healing and bone regeneration and problems in tissue engineering
have been an active area for mathematical modeling in the last decade. Here we review a …

If improvements are to be made in tuberculosis (TB) treatment, an increased understanding
of disease in the lung is needed. Studies have shown that bacteria in a less metabolically …