Meta-analysis of probability estimates of worldwide variation of CYP2D6 and CYP2C19
AB Koopmans, MH Braakman, DJ Vinkers… - Translational …, 2021 - nature.com
Extensive migration has led to the necessity of knowledge regarding the treatment of
migrants with different ethnical backgrounds. This is especially relevant for pharmacological …
migrants with different ethnical backgrounds. This is especially relevant for pharmacological …
The future of personalized medicine in space: from observations to countermeasures
E Pavez Loriè, S Baatout, A Choukér… - … in bioengineering and …, 2021 - frontiersin.org
The aim of personalized medicine is to detach from a “one-size fits all approach” and
improve patient health by individualization to achieve the best outcomes in disease …
improve patient health by individualization to achieve the best outcomes in disease …
Polymorphism in CYP 2D6 and CYP 2C19, members of the cytochrome P450 mixed‐function oxidase system, in the metabolism of psychotropic drugs
J Stingl, R Viviani - Journal of internal medicine, 2015 - Wiley Online Library
Numerous studies in the field of psychopharmacological treatment have investigated the
possible contribution of genetic variability between individuals to differences in drug efficacy …
possible contribution of genetic variability between individuals to differences in drug efficacy …
Pharmacogenetic tests to guide drug treatment in depression: comparison of the available testing kits and clinical trials
The empirical approach to drug choice and dosing in depression often results into
inadequate response and side effects. Pharmacogenetic (PGx) testing appears a promising …
inadequate response and side effects. Pharmacogenetic (PGx) testing appears a promising …
[HTML][HTML] A naturalistic study of the effectiveness of pharmacogenetic testing to guide treatment in psychiatric patients with mood and anxiety disorders
FX Brennan, KR Gardner, J Lombard… - The primary care …, 2015 - psychiatrist.com
Objective: To examine the effectiveness of genetic testing in a real-world setting and to
assess its impact on clinician treatment decisions. Method: This was a naturalistic …
assess its impact on clinician treatment decisions. Method: This was a naturalistic …
The promise of psychiatric pharmacogenomics
SP Hamilton - Biological Psychiatry, 2015 - Elsevier
Clinicians already face “personalized” medicine every day while experiencing the great
variation in toxicities and drug efficacy among individual patients. Pharmacogenetics studies …
variation in toxicities and drug efficacy among individual patients. Pharmacogenetics studies …
Pharmacogenetic testing of cytochrome P450 drug metabolizing enzymes in a case series of patients with Prader-Willi syndrome
J Forster, J Duis, MG Butler - Genes, 2021 - mdpi.com
Prader-Willi syndrome (PWS) is associated with co-morbid psychiatric symptoms (disruptive
behavior, anxiety, mood disorders, and psychosis) often requiring psychotropic medications …
behavior, anxiety, mood disorders, and psychosis) often requiring psychotropic medications …
Risperidone and venlafaxine metabolic ratios strongly predict a CYP2D6 poor metabolizing genotype
B Mannheimer, T Haslemo, JD Lindh… - Therapeutic drug …, 2016 - journals.lww.com
Purpose: To investigate the predictive value of the risperidone and venlafaxine metabolic
ratios and CYP2D6 genotype. Methods: The determination of risperidone, 9 …
ratios and CYP2D6 genotype. Methods: The determination of risperidone, 9 …
Antidepressant pharmacogenetics
Early reports of clinical utility are published. The current evidence base for antidepressant
pharmacogenetics is, however, not yet empirically robust enough to inform routine …
pharmacogenetics is, however, not yet empirically robust enough to inform routine …
Time in treatment: Examining mental illness trajectories across inpatient psychiatric treatment
Early discharge or reduced length of stay for inpatient psychiatric patients is related to
increased readmission rates and worse clinical outcomes including increased risk for …
increased readmission rates and worse clinical outcomes including increased risk for …