[PDF][PDF] The mechanisms of action of Tumor Treating Fields

JC Moser, E Salvador, K Deniz, K Swanson… - Cancer research, 2022 - AACR
Abstract Tumor Treating Fields (TTFields), a new modality of cancer treatment, are electric
fields transmitted transdermally to tumors. The FDA has approved TTFields for the treatment …

Tumor-treating fields in glioblastomas: past, present, and future

X Guo, X Yang, J Wu, H Yang, Y Li, J Li, Q Liu, C Wu… - Cancers, 2022 - mdpi.com
Simple Summary Glioblastoma (GBM) is the most common malignant primary brain tumor.
Although the standard of care, including maximal resection, concurrent radiotherapy with …

Electrotherapies for glioblastoma

EPW Jenkins, A Finch, M Gerigk, IF Triantis… - Advanced …, 2021 - Wiley Online Library
Abstract Non‐thermal, intermediate frequency (100–500 kHz) electrotherapies present a
unique therapeutic strategy to treat malignant neoplasms. Here, pulsed electric fields (PEFs) …

Permeabilizing cell membranes with electric fields

AA Aguilar, MC Ho, E Chang, KW Carlson, A Natarajan… - Cancers, 2021 - mdpi.com
Simple Summary The FDA recently approved a fourth approach (in addition to surgery,
radiation therapy, and chemotherapy) for treating glioblastoma; namely, tumor treating fields …

Tumor treating fields: at the crossroads between physics and biology for cancer treatment

FA Carrieri, C Smack, I Siddiqui, LR Kleinberg… - Frontiers in …, 2020 - frontiersin.org
Despite extraordinary advances that have been achieved in the last few decades, cancer
continues to represent a leading cause of mortality worldwide. Lethal cancer types ultimately …

Tumor treating fields: a comprehensive overview of the underlying molecular mechanism

P Hong, N Kudulaiti, S Wu, J Nie… - Expert review of …, 2022 - Taylor & Francis
Introduction As a novel treatment modality, tumor treating fields (TTFields) exert low-
intensity, medium-frequency electric fields on tumor cells. TTFields' effectiveness and safety …

Tumor-Treating Fields: A fourth modality in cancer treatment, new practice updates

R Arvind, SR Chandana, MJ Borad… - Critical Reviews in …, 2021 - Elsevier
Although major innovations in treatment are advancing, cancer persists as one of the
leading causes of mortality. With the rising incidence of cancer and as we treat them …

Insight into the surface discharge cold plasma efficient inactivation of Pseudomonas fluorescens in water based on exogenous reactive oxygen and nitrogen species …

JB Ni, CJ Ding, JS Zhang, XM Fang, HW Xiao - Journal of Hazardous …, 2024 - Elsevier
As well known, surface discharge cold plasma has efficient inactivation ability and a variety
of RONS are main active particles for inactivation, but their synergistic mechanism is still not …

A review of tumor treating fields (TTFields): advancements in clinical applications and mechanistic insights

X Li, K Liu, L Xing, B Rubinsky - Radiology and Oncology, 2023 - sciendo.com
Background. Tumor Treating Fields (TTFields) is a non-invasive modality for cancer
treatment that utilizes a specific sinusoidal electric field ranging from 100 kHz to 300 kHz …

Aurora B kinase inhibition by AZD1152 concomitant with tumor treating fields is effective in the treatment of cultures from primary and recurrent glioblastomas

D Krex, P Bartmann, D Lachmann, A Hagstotz… - International Journal of …, 2023 - mdpi.com
Tumor Treating Fields (TTFields) were incorporated into the treatment of glioblastoma, the
most malignant brain tumor, after showing an effect on progression-free and overall survival …