Inflammatory responses and inflammation-associated diseases in organs

L Chen, H Deng, H Cui, J Fang, Z Zuo, J Deng… - …, 2017 - pmc.ncbi.nlm.nih.gov
Inflammation is a biological response of the immune system that can be triggered by a
variety of factors, including pathogens, damaged cells and toxic compounds. These factors …

Properties and functions of fibroblasts and myofibroblasts in myocardial infarction

H Venugopal, A Hanna, C Humeres, NG Frangogiannis - Cells, 2022 - mdpi.com
The adult mammalian heart contains abundant interstitial and perivascular fibroblasts that
expand following injury and play a reparative role but also contribute to maladaptive fibrotic …

ST-segment elevation myocardial infarction

B Vogel, BE Claessen, SV Arnold, D Chan… - Nature reviews Disease …, 2019 - nature.com
ST-segment elevation myocardial infarction (STEMI) is the most acute manifestation of
coronary artery disease and is associated with great morbidity and mortality. A complete …

Guidelines for experimental models of myocardial ischemia and infarction

ML Lindsey, R Bolli, JM Canty Jr… - American Journal …, 2018 - journals.physiology.org
Myocardial infarction is a prevalent major cardiovascular event that arises from myocardial
ischemia with or without reperfusion, and basic and translational research is needed to …

A double-edged sword of immuno-microenvironment in cardiac homeostasis and injury repair

K Sun, Y Li, J Jin - Signal transduction and targeted therapy, 2021 - nature.com
The response of immune cells in cardiac injury is divided into three continuous phases:
inflammation, proliferation and maturation. The kinetics of the inflammatory and proliferation …

Pathophysiology of myocardial infarction

NG Frangogiannis - Comprehensive Physiology, 2011 - Wiley Online Library
Myocardial infarction is defined as sudden ischemic death of myocardial tissue. In the
clinical context, myocardial infarction is usually due to thrombotic occlusion of a coronary …

[图书][B] Excitation-contraction coupling and cardiac contractile force

D Bers - 2001 - books.google.com
How is the heartbeat generated? What controls the strength of contraction of heart muscle?
What are the links between cardiac structure and function? How does our understanding of …

Brain vulnerability and viability after ischaemia

SG Daniele, G Trummer, KA Hossmann… - Nature Reviews …, 2021 - nature.com
The susceptibility of the brain to ischaemic injury dramatically limits its viability following
interruptions in blood flow. However, data from studies of dissociated cells, tissue …

Extensive scar formation and regression during heart regeneration after cryoinjury in zebrafish

JM González-Rosa, V Martín, M Peralta… - …, 2011 - journals.biologists.com
The zebrafish heart has the capacity to regenerate after ventricular resection. Although this
regeneration model has proved useful for the elucidation of certain regeneration …

The immune system and cardiac repair

NG Frangogiannis - Pharmacological research, 2008 - Elsevier
Myocardial infarction is the most common cause of cardiac injury and results in acute loss of
a large number of myocardial cells. Because the heart has negligible regenerative capacity …