The Diversity of Escherichia coli Pathotypes and Vaccination Strategies against This Versatile Bacterial Pathogen
Escherichia coli (E. coli) is a gram-negative bacillus and resident of the normal intestinal
microbiota. However, some E. coli strains can cause diseases in humans, other mammals …
microbiota. However, some E. coli strains can cause diseases in humans, other mammals …
Recent advances in understanding enteric pathogenic Escherichia coli
Although Escherichia coli can be an innocuous resident of the gastrointestinal tract, it also
has the pathogenic capacity to cause significant diarrheal and extraintestinal diseases …
has the pathogenic capacity to cause significant diarrheal and extraintestinal diseases …
Intestinal Pathogenic Escherichia coli: Insights for Vaccine Development
Diarrheal diseases are one of the major causes of mortality among children under five years
old and intestinal pathogenic Escherichia coli (InPEC) plays a role as one of the large …
old and intestinal pathogenic Escherichia coli (InPEC) plays a role as one of the large …
Pre-existing immunity against vaccine vectors–friend or foe?
M Saxena, TTH Van, FJ Baird, PJ Coloe… - …, 2013 - microbiologyresearch.org
Over the last century, the successful attenuation of multiple bacterial and viral pathogens
has led to an effective, robust and safe form of vaccination. Recently, these vaccines have …
has led to an effective, robust and safe form of vaccination. Recently, these vaccines have …
[HTML][HTML] Development and preclinical evaluation of safety and immunogenicity of an oral ETEC vaccine containing inactivated E. coli bacteria overexpressing …
J Holmgren, L Bourgeois, N Carlin, J Clements… - Vaccine, 2013 - Elsevier
A first-generation oral inactivated whole-cell enterotoxigenic Escherichia coli (ETEC)
vaccine, comprising formalin-killed ETEC bacteria expressing different colonization factor …
vaccine, comprising formalin-killed ETEC bacteria expressing different colonization factor …
Recent progress toward an enterotoxigenic Escherichia coli vaccine
AM Svennerholm, A Lundgren - Expert review of vaccines, 2012 - Taylor & Francis
Enterotoxigenic Escherichia coli (ETEC) is the most common cause of bacterial diarrhea in
children in Africa, Asia and Latin America and in travelers to these regions. Despite this, no …
children in Africa, Asia and Latin America and in travelers to these regions. Despite this, no …
From cholera to enterotoxigenic Escherichia coli (ETEC) vaccine development
AM Svennerholm - Indian Journal of Medical Research, 2011 - journals.lww.com
It was shown earlier that immune responses against cholera toxin (CT) as well as Vibrio
cholerae lipopolysaccharide (LPS) or whole bacterial cells (WC) were protective and that …
cholerae lipopolysaccharide (LPS) or whole bacterial cells (WC) were protective and that …
A combined vaccine approach against Vibrio cholerae and ETEC based on outer membrane vesicles
DR Leitner, S Lichtenegger, P Temel, FG Zingl… - Frontiers in …, 2015 - frontiersin.org
Enteric infections induced by pathogens like Vibrio cholerae and enterotoxigenic
Escherichia coli (ETEC) remain a massive burden in developing countries with increasing …
Escherichia coli (ETEC) remain a massive burden in developing countries with increasing …
The Adjuvant Double Mutant Escherichia coli Heat Labile Toxin Enhances IL-17A Production in Human T Cells Specific for Bacterial Vaccine Antigens
S Leach, JD Clements, J Kaim, A Lundgren - PloS one, 2012 - journals.plos.org
The strong adjuvant activity and low enterotoxicity of the novel mucosal adjuvant double
mutant Escherichia coli heat labile toxin, LT (R192G/L211A) or dmLT, demonstrated in mice …
mutant Escherichia coli heat labile toxin, LT (R192G/L211A) or dmLT, demonstrated in mice …
Development of Stable Vibrio cholerae O1 Hikojima Type Vaccine Strains Co–Expressing the Inaba and Ogawa Lipopolysaccharide Antigens
We describe here the development of stable classical and El Tor V. cholerae O1 strains of
the Hikojima serotype that co–express the Inaba and Ogawa antigens of O1 …
the Hikojima serotype that co–express the Inaba and Ogawa antigens of O1 …