It has been noticed in recent years that the unfavorable effects of the gut microbiota could
exhaust host vigor and life, yet knowledge and theory are just beginning to be established …

The blood-brain barrier (BBB) prevents neurotoxic plasma components, blood cells, and
pathogens from entering the brain. At the same time, the BBB regulates transport of …

Epilepsy, a neurological disease characterized by recurrent seizures, is often associated
with a history of previous lesions in the nervous system. Impaired regulation of the activation …

Ischaemic stroke involves the rapid onset of focal neurological dysfunction, most commonly
due to an arterial blockage in a specific region of the brain. Stroke is a leading cause of …

Central nervous system (CNS) barriers predominantly mediate the immune-privileged status
of the brain, and are also important regulators of neuroimmune communication. It is …

Over the last decades, considerable efforts have been put into developing active nanocarrier
systems that cross the blood brain barrier (BBB) to treat brain-related diseases such as …

Endothelial cells are at the interface between circulating blood and tissues. This position
confers on them a crucial role in controlling oxygen and nutrient exchange and cellular …

The peripheral (PNS) and central nervous system (CNS) are delicate structures, highly
sensitive to homeostatic changes—and crucial for basic vital functions. Thus, a selection of …

High parameter imaging is an important tool in the life sciences for both discovery and
healthcare applications. Imaging Mass Cytometry (IMC) and Multiplexed Ion Beam Imaging …

Subarachnoid hemorrhage (SAH) is a type of stroke with high morbidity and mortality. Netrin-
1 (NTN-1) can alleviate early brain injury (EBI) following SAH by enhancing peroxisome …