Dendritic spines are small, thin, specialized protrusions from neuronal dendrites, primarily
localized in the excitatory synapses. Sophisticated imaging techniques revealed that …

Abnormalities in dendritic spines have commonly been observed in brain specimens from
epilepsy patients and animal models of epilepsy. However, the functional implications and …

It has been postulated that chronic administration of antidepressant drugs induces delayed
structural and molecular adaptations at glutamatergic forebrain synapses that might underlie …

Dendritic spines are the locus for excitatory synaptic transmission in the brain and thus play
a major role in neuronal plasticity. The ability to alter synaptic connections includes …

The retrosplenial cortex (RSC) is reciprocally connected with the hippocampus and various
parahippocampal cortical regions, suggesting that RSC is well‐positioned to contribute to …

BACKGROUND: Obstetric complications, particularly fetal hypoxia, are associated with
increased risk for schizophrenia later in life. Such factors are also related to increased …

Purpose To determine whether developmental synaptic pruning defects in epileptic C1q‐
knockout (KO) mice are accompanied by postsynaptic abnormalities in dendrites and/or …

Antidepressant drugs are usually administered for several weeks for the treatment of major
depressive disorder. However, they are also prescribed in several additional psychiatric …

Sleep-related hypermotor epilepsy (SHE) is a group of clinical syndromes with
heterogeneous etiologies. SHE is difficult to diagnose and treat in the early stages due to its …

Dendritic spines are cellular specializations that greatly increase the connectivity of neurons
and modulate the “weight” of most postsynaptic excitatory potentials. Spines are found in …