Fabrication, evaluation and applications of dissolving microneedles

L Zhang, R Guo, S Wang, X Yang, G Ling… - International journal of …, 2021 - Elsevier
In recent years, transdermal preparations have emerged as one of the most promising
modes of administration. In particular, dissolving microneedles have attracted extensive …

[HTML][HTML] Trends in drug-and vaccine-based dissolvable microneedle materials and methods of fabrication

LE Moore, S Vucen, AC Moore - European Journal of Pharmaceutics and …, 2022 - Elsevier
Microneedle patches, also called microarray patches (MAP), are an emerging technology for
delivery and sampling of drugs, vaccines and other materials. This review focuses on the …

Recent progress in PLGA-based microneedle-mediated transdermal drug and vaccine delivery

A Malek-Khatabi, MS Razavi, A Abdollahi… - Biomaterials …, 2023 - pubs.rsc.org
Microneedles (MNs) have recently been found to have applications in drug, vitamin, protein
and vaccine delivery. Polymeric MN arrays continue to attract increasing attention due to …

Development of polyvinylpyrrolidone-based nanomaterials for biosensors applications: a review

M Pourmadadi, A Shamsabadipour, A Aslani… - Inorganic Chemistry …, 2023 - Elsevier
A biosensor is an analytical tool applied for biomarkers' specific and sensitive detection.
Using biosensors in clinical settings leads to trustworthy, precise, and quantitative …

Polymeric microneedles for transdermal drug delivery-a review of recent studies

Z Karim, P Karwa, SRR Hiremath - Journal of Drug Delivery Science and …, 2022 - Elsevier
Transdermal drug delivery is contemplated as one of the top appealing routes for
pharmaceutically active ingredients administration owing to the several benefits, specifically …

A dual-delivery platform for vaccination using antigen-loaded nanoparticles in dissolving microneedles

KB Gomes, B D'Souza, S Vijayanand, I Menon… - International Journal of …, 2022 - Elsevier
Effective vaccines delivered via painless methods would revolutionize the way people
approach vaccinations. This study focused on the development of fast-dissolving …

A Diruthenium Metallodrug as a Potent Inhibitor of Amyloid-β Aggregation: Synergism of Mechanisms of Action

S La Manna, C Di Natale, V Panzetta, M Leone… - Inorganic …, 2023 - ACS Publications
The physical and chemical properties of paddlewheel diruthenium compounds are highly
dependent on the nature of the ligands surrounding the bimetallic core. Herein, we compare …

Highly prolonged release of the cancer vaccine and immunomodulator via a two-layer biodegradable microneedle for prophylactic treatment of metastatic cancer

HTT Duong, Y Yin, TMD Le, JH Jeong… - …, 2023 - ACS Publications
Simultaneous sustained release of cancer vaccines and immunomodulators may effectively
trigger durable immune responses and avoid multiple administrations. Here, we established …

Preparation, characterisation and comparison of glabridin-loaded hydrogel-forming microneedles by chemical and physical cross-linking

X Pan, Y Li, W Pang, Y Xue, Z Wang, C Jiang… - International Journal of …, 2022 - Elsevier
Abstract Poly (vinyl alcohol)(PVA) and carbomer were used as the hydrogel system to
fabricate glabridin-loaded hydrogel-forming microneedles (HFMNs) by chemical cross …

Recent fabrication methods to produce polymer-based drug delivery matrices (Experimental and In Silico Approaches)

A Procopio, E Lagreca, R Jamaledin, S La Manna… - Pharmaceutics, 2022 - mdpi.com
The study of novel drug delivery systems represents one of the frontiers of the biomedical
research area. Multi-disciplinary scientific approaches combining traditional or engineered …