Abstract O-linked-N-acetylglucosaminylation (O-GlcNAcylation) is a type of glycosylation that
occurs when a monosaccharide, O-GlcNAc, is added onto serine or threonine residues of …

O-GlcNAcylation is a post-translational modification occurring on serine/threonine residues
of nuclear and cytoplasmic proteins, mediated by the enzymes OGT and OGA which …

The aim of the current study was to investigate the effects of glucosamine (GlcN) on septic
lethality and sepsis-induced inflammation using animal models of mice and zebrafish. GlcN …

Macrophages are a type of functionally plastic cells that can create a pro-/anti-inflammatory
microenvironment for organs by producing different kinds of cytokines, chemokines, and …

Chronic, low‑grade inflammation associated with obesity and diabetes result from the
infiltration of adipose and vascular tissue by immune cells and contributes to cardiovascular …

Impaired brain glucose metabolism is considered a hallmark of brain dysfunction and
neurodegeneration. Disruption of the hexosamine biosynthetic pathway (HBP) and …

Purpose Oxidative stress and inflammation are key pathophysiological features of chronic
respiratory diseases, including asthma and chronic obstructive pulmonary disease (COPD) …

O-Linked β-N-acetylglucosamine (O-GlcNAc) is an essential, dynamic monosaccharide post-
translational modification (PTM) found on serine and threonine residues of thousands of …

Label-free single-cell analytics have been developed for understanding the collective
immune response mechanism of immune cells. However, it remains difficult to analyze the …

Sepsis is a systemic inflammatory response syndrome (SIRS) resulting from a severe
infection that is characterized by immune dysregulation, cardiovascular derangements, and …