Intraventricular hemorrhage is one of the most fatal forms of brain injury that is a common
complication of premature infants. However, the therapy of this type of hemorrhage is limited …

Objectives To explore, based on the existing body of literature, main characteristics of
prenatal counseling for parents at risk for extreme preterm birth. Methods A scoping review …

Bacterial infections are a major cause of mortality in preterm babies, yet our understanding
of early-life disease-associated immune dysregulation remains limited. Here, we combine …

Extremely preterm birth before 28 weeks' gestation accounts for less than 1% of births in
high-income countries but is associated with high rates of perinatal and infant mortality, and …

Background Reduced insulin-like growth factor-1 (IGF-1) levels may contribute to impaired
organ development in preterm infants. Using preterm pigs as a model, we hypothesized that …

Perinatal white matter injury (PWMI) can lead to permanent neurological damage in preterm
infants and bring a huge economic burden to their families and society. Liver X receptors …

Importance Understanding why and how extremely preterm infants die is important for
practitioners caring for these infants. Objective To examine risk factors, causes, timing, and …

The current Dutch guideline on care at the edge of perinatal viability advises to consider
initiation of active care to infants born from 24 weeks of gestational age on. This, only after …

Intraventricular hemorrhage (IVH) is a serious concern for preterm infants and can
predispose such infants to brain injury and poor neurodevelopmental outcomes. IVH is …

Introduction. Mortality in very low birth weight infants (VLBWIs) has remained at~ 26% in the
past 16 years in the NEOCOSUR Neonatal Network. Objective. To determine the cause of …