G protein-coupled receptors (GPCRs) are the largest family of membrane-bound receptors
and also the targets of many drugs. Understanding of the functional significance of the wide …

Odour perception is initiated by specific interactions between odorants and a large
repertoire of receptors in olfactory neurons. During the past few years, considerable …

The human genome holds an extraordinary trove of information about human development,
physiology, medicine and evolution. Here we report the results of an international …

Olfactory receptor (OR) genes are the largest gene superfamily in vertebrates. We have
identified the mouse OR genes from the nearly complete Celera mouse genome by a …

Humans perceive an immense variety of chemicals as having distinct odors. Odor
perception initiates in the nose, where odorants are detected by a large family of olfactory …

Although it has been known for some time that olfactory receptors (ORs) reside in
spermatozoa, the function of these ORs is unknown. Here, we identified, cloned, and …

Olfactory receptors likely constitute the largest gene superfamily in the vertebrate genome.
Here we present the nearly complete human olfactory subgenome elucidated by mining the …

Olfactory receptors (ORs) provide the molecular basis for the detection of volatile odorant
molecules by olfactory sensory neurons. The OR supergene family encodes G-protein …

The human genome holds an extraordinary trove of information about human development,
physiology, medicine and evolution. Here we report the results of an international …

Background The mammalian olfactory apparatus is able to recognize and distinguish
thousands of structurally diverse volatile chemicals. This chemosensory function is mediated …