Conventional in vitro tests to assess the aerodynamic particle size distribution (APSD) from
inhaler devices use simple right-angle inlets (“mouth-throats”, MTs) to cascade impactors …

Phage cocktail broadens the host range compared with a single phage and minimizes the
development of phage-resistant bacteria thereby promoting the long-term usefulness of …

Abstract Background Computational Fluid-Particle Dynamics (CFPD) models have been
employed to predict lung aerosol dynamics for decades, estimating the delivery efficiency of …

Developing novel drug formulations and progressing them to the clinical environment relies
on preclinical in vitro studies and animal tests to evaluate efficacy and toxicity. However …

Pulmonary delivery is an efficient route of administration to deliver cannabidiol (CBD) due to
the high bioavailability and fast onset of action. The major formulation challenge is the poor …

Aerosol drug delivery in the human airway is significantly affected by the morphology and
size of the airway. This work developed a CFD-DEM model to simulate and analyze air flow …

Jojoba (Simmondsia chinensis (Link) CK Schneid) is a dioecious plant in desert and semi-
desert areas, eg, the Ismailia Desert in Egypt. Jojoba oil (JJBO) is a natural slight yellow oil …

Understanding the impact of inhaler mouthpiece sizes on particle transport and deposition in
the human upper airway is important to optimize inhaler designs toward improving the …

This study aims to systematically isolate different anatomical features of the human pharynx
with the goal to investigate their independent influence on airflow dynamics and particle …

The influence of grid generated mixing on the fluidization of pharmaceutical carrier powders
is studied in a channel-flow experiment using direct high-speed imaging and particle image …