Pharmacological properties and molecular mechanisms of thymol: prospects for its therapeutic potential and pharmaceutical development

MF Nagoor Meeran, H Javed, H Al Taee… - Frontiers in …, 2017 - frontiersin.org
Thymol, chemically known as 2-isopropyl-5-methylphenol is a colorless crystalline
monoterpene phenol. It is one of the most important dietary constituents in thyme species …

[HTML][HTML] Mammalian transient receptor potential TRPA1 channels: from structure to disease

K Talavera, JB Startek, J Alvarez-Collazo… - Physiological …, 2020 - journals.physiology.org
The transient receptor potential ankyrin (TRPA) channels are Ca 2+-permeable nonselective
cation channels remarkably conserved through the animal kingdom. Mammals have only …

TRPA1 as a therapeutic target for nociceptive pain

D Souza Monteiro de Araujo, R Nassini… - Expert opinion on …, 2020 - Taylor & Francis
Introduction Chronic pain affects approximatively 30–50% of the population globally.
Pathologies such as migraine, diabetic neuropathy, nerve injury and treatment with …

Transient receptor potential (TRP) channels: a clinical perspective

Y Kaneko, A Szallasi - British journal of pharmacology, 2014 - Wiley Online Library
Transient receptor potential (TRP) channels are important mediators of sensory signals with
marked effects on cellular functions and signalling pathways. Indeed, mutations in genes …

Control of biogenic amines in food—existing and emerging approaches

A Naila, S Flint, G Fletcher, P Bremer… - Journal of food …, 2010 - Wiley Online Library
Biogenic amines have been reported in a variety of foods, such as fish, meat, cheese,
vegetables, and wines. They are described as low molecular weight organic bases with …

The transient receptor potential channel TRPA1: from gene to pathophysiology

B Nilius, G Appendino, G Owsianik - Pflügers Archiv-European Journal of …, 2012 - Springer
Abstract The Transient Receptor Potential Ankyrin 1 channel (TRPA1), is a member of the
large TRP family of ion channels, and functions as a Ca 2+ permeable non-selective cation …

Phytogenic bioactive compounds shape fish mucosal immunity

JP Firmino, J Galindo-Villegas… - Frontiers in …, 2021 - frontiersin.org
Aquaculture growth will unavoidably involve the implementation of innovative and
sustainable production strategies, being functional feeds among the most promising ones. A …

Trpa1

PM Zygmunt, ED Högestätt - … potential (TRP) cation channels: volume I, 2014 - Springer
The transient receptor potential ankyrin subtype 1 protein (TRPA1) is a nonselective cation
channel permeable to Ca 2+, Na+, and K+. TRPA1 is a promiscuous chemical nocisensor …

TRPA1: a molecular view

JE Meents, CI Ciotu… - Journal of …, 2019 - journals.physiology.org
The transient receptor potential ankyrin 1 (TRPA1) ion channel is expressed in pain-sensing
neurons and other tissues and has become a major target in the development of novel …

The TRPA1 channel in inflammatory and neuropathic pain and migraine

R Nassini, S Materazzi, S Benemei… - Reviews of Physiology …, 2014 - Springer
The transient receptor potential ankyrin 1 (TRPA1), a member of the TRP superfamily of
channels, is primarily localized to a subpopulation of primary sensory neurons of the …