Neuronal and glial CSF biomarkers in multiple sclerosis: A systematic review and meta-analysis

S Momtazmanesh, P Shobeiri… - Reviews in the …, 2021 - degruyter.com
Multiple sclerosis (MS) is a neurodegenerative disease associated with inflammatory
demyelination and astroglial activation, with neuronal and axonal damage as the leading …

Biological markers in CSF and blood for axonal degeneration in multiple sclerosis

CE Teunissen, C Dijkstra, C Polman - The Lancet Neurology, 2005 - thelancet.com
Biomarkers in body fluids could help to predict and monitor neurological decline in people
with multiple sclerosis (MS). We discuss markers for axonal damage in body fluids in people …

Cerebrospinal fluid tau and β-amyloid: how well do these biomarkers reflect autopsy-confirmed dementia diagnoses?

CM Clark, S Xie, J Chittams, D Ewbank… - Archives of …, 2003 - jamanetwork.com
Background Tau and β-amyloid (Aβ) are proposed diagnostic biomarkers for Alzheimer
disease (AD). Previous studies report their relationship to clinical diagnoses of AD and other …

Axonal damage markers in cerebrospinal fluid are increased in ALS

J Brettschneider, A Petzold, SD Sussmuth… - Neurology, 2006 - AAN Enterprises
Objective: To test whether biomarkers for axonal degeneration correlated with clinical
subtypes and were of use in predicting progression of ALS. Methods: Patients with ALS (n …

Axonal damage in multiple sclerosis

JD Haines, M Inglese… - Mount Sinai Journal of …, 2011 - Wiley Online Library
Multiple sclerosis is a debilitating disease of the central nervous system that has been
characteristically classified as an immune‐mediated destruction of myelin, the protective …

Alzheimer disease: current concepts and emerging diagnostic and therapeutic strategies

CM Clark, JHT Karlawish - Annals of internal medicine, 2003 - acpjournals.org
Alzheimer disease is a complex neurodegenerative dementing illness. It has become a
major public health problem because of its increasing prevalence, long duration, high cost of …

Cerebrospinal fluid biomarkers and cognitive functions at multiple sclerosis diagnosis

E Virgilio, D Vecchio, I Crespi, C Puricelli, P Barbero… - Journal of …, 2022 - Springer
Cognitive impairment (CI) is a frequent and disabling symptom in Multiple Sclerosis (MS).
Axonal damage may contribute to CI development from early stages. Nevertheless, no …

Disease biomarkers in multiple sclerosis: potential for use in therapeutic decision making

VK Harris, SA Sadiq - Molecular diagnosis & therapy, 2009 - Springer
Multiple sclerosis (MS) is an autoimmune disorder of the brain and spinal cord that
predominantly affects white matter. MS has a variable clinical presentation and has no …

The role of Tau beyond Alzheimer's disease: a narrative review

E Virgilio, F De Marchi, E Contaldi, U Dianzani… - Biomedicines, 2022 - mdpi.com
Nowadays, there is a need for reliable fluid biomarkers to improve differential diagnosis,
prognosis, and the prediction of treatment response, particularly in the management of …

Highly increased CSF tau protein and decreased β-amyloid (1–42) in sporadic CJD: a discrimination from Alzheimer's disease?

E Kapaki, K Kilidireas, GP Paraskevas… - Journal of Neurology …, 2001 - jnnp.bmj.com
The aim was to quantify tau protein and β-amyloid (Aβ42) in the CSF of patients with
sporadic Creutzfeldt-Jakob disease (CJD), Alzheimer's disease (AD), and controls. Double …