Pre-eclampsia part 1: current understanding of its pathophysiology

T Chaiworapongsa, P Chaemsaithong, L Yeo… - Nature Reviews …, 2014 - nature.com
Pre-eclampsia is characterized by new-onset hypertension and proteinuria at≥ 20 weeks of
gestation. In the absence of proteinuria, hypertension together with evidence of systemic …

[HTML][HTML] Preeclampsia: novel mechanisms and potential therapeutic approaches

Z Armaly, JE Jadaon, A Jabbour, ZA Abassi - Frontiers in physiology, 2018 - frontiersin.org
Preeclampsia is a serious complication of pregnancy where it affects 5–8% of all
pregnancies. It increases the morbidity and mortality of both the fetus and pregnant woman …

Preeclampsia in 2018: revisiting concepts, physiopathology, and prediction

J Mayrink, ML Costa, JG Cecatti - The Scientific World Journal, 2018 - Wiley Online Library
Preeclampsia currently remains one of the leading causes of death and severe maternal
morbidity. Although its prevalence is still underestimated in some places due to …

Proteinuria during pregnancy: definition, pathophysiology, methodology, and clinical significance

MF Bartal, MD Lindheimer, BM Sibai - American journal of obstetrics and …, 2022 - Elsevier
Qualitative and quantitative measurement of urine protein excretion is one of the most
common tests performed during pregnancy. For more than 100 years, proteinuria was …

A potential role for mechanical forces in the detachment of podocytes and the progression of CKD

W Kriz, KV Lemley - Journal of the American Society of …, 2015 - journals.lww.com
Loss of podocytes underlies progression of CKD. Detachment of podocytes from the
glomerular basement membrane (GBM) rather than apoptosis or necrosis seems to be the …

Preeclampsia: long-term consequences for vascular health

LM Amaral, MW Cunningham Jr… - Vascular health and …, 2015 - Taylor & Francis
Preeclampsia (PE) is a pregnancy-specific syndrome and one of the leading causes of
preterm birth, neonatal and maternal morbidity and mortality. This disease is characterized …

[HTML][HTML] Oxidative stress in preeclampsia and the role of free fetal hemoglobin

SR Hansson, Å Nääv, L Erlandsson - Frontiers in physiology, 2015 - frontiersin.org
Preeclampsia is a leading cause of pregnancy complications and affects 3–7% of pregnant
women. This review summarizes the current knowledge of a new potential etiology of the …

Preeclampsia and kidney disease: deciphering cause and effect

A Kattah - Current hypertension reports, 2020 - Springer
Abstract Purpose of Review Preeclampsia and chronic kidney disease have a complex,
bidirectional relationship. Women with kidney disease, with even mild reductions in …

[HTML][HTML] Preeclampsia: a close look at renal dysfunction

HM Sani, SZ Vahed, M Ardalan - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Preeclampsia (PE) is a unique pathophysiologic situation that physiologic interests of
mother, fetus, and placenta diverge. PE is related to the increased circulating antiangiogenic …

Hypertensive nephropathy. Moving from classic to emerging pathogenetic mechanisms

TM Seccia, B Caroccia, LA Calò - Journal of hypertension, 2017 - journals.lww.com
Hypertensive kidney disease classically entails nephroangiosclerosis and hyalinosis with
glomerular damage. However, in recent years, several evidences showed that high blood …