Molecular profile of driver genes in lung adenocarcinomas of Brazilian patients who have never smoked: implications for targeted therapies
RO Cavagna, F Escremim de Paula… - The …, 2024 - academic.oup.com
Introduction Lung cancer in never-smoker (LCINS) patients accounts for 20% of lung cancer
cases, and its biology remains poorly understood, particularly in genetically admixed …
cases, and its biology remains poorly understood, particularly in genetically admixed …
Single-Cell Analysis Differentiates the Effects of p53 Mutation and p53 Loss on Cell Compositions of Oncogenic Kras-Driven Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDAC) is a devastating malignant disease with a dismal
prognosis. In the past decades, a plethora of genetically engineered mouse models …
prognosis. In the past decades, a plethora of genetically engineered mouse models …
Association of ESR1 Germline Variants with TP53 Somatic Variants in Breast Tumors in a Genome-wide Study
NP Tjader, AJ Beer, J Ramroop, MC Tai… - Cancer research …, 2024 - aacrjournals.org
In breast tumors, somatic mutation frequencies in TP53 and PIK3CA vary by tumor subtype
and ancestry. Emerging data suggest tumor mutation status is associated with germline …
and ancestry. Emerging data suggest tumor mutation status is associated with germline …