Benzodiazepines and antidepressants: Effects on cognitive and functional decline in Alzheimer's disease and Lewy body dementia

MG Borda, A Jaramillo‐Jimenez… - … Journal of Geriatric …, 2021 - Wiley Online Library
Objectives We aim to study the effects of the prescription of benzodiazepines and
antidepressants on cognitive and functional decline in older adults living with Alzheimer's …

Association of malnutrition with functional and cognitive trajectories in people living with dementia: a five-year follow-up study

MG Borda, AM Ayala Copete… - Journal of …, 2021 - content.iospress.com
Background: In dementia, functional status depends on multiple factors in addition to
cognition. Nutritional status is a potentially modifiable factor related to homeostasis and …

Characterization of apathy-like behaviors in the 5xFAD mouse model of Alzheimer's disease

R Keszycki, G Rodriguez, JT Dunn, A Locci… - Neurobiology of …, 2023 - Elsevier
Most patients with Alzheimer's disease (AD) develop neuropsychiatric symptoms (NPS)
alongside cognitive decline, and apathy is one of the most common symptoms. Few …

Specific agitation behaviours in dementia differentially contribute to aspects of caregiver burden

KS Patrick, J Gunstad, JT Martin, KR Chapman… - …, 2022 - Wiley Online Library
Background Agitation is a common symptom in dementia and linked to caregiver burden, but
both agitation and burden are multidimensional constructs. The current study sought to …

Polypharmacy is associated with functional decline in Alzheimer's disease and Lewy body dementia

MG Borda, N Castellanos-Perilla, DA Tovar-Rios… - Archives of gerontology …, 2021 - Elsevier
Background In dementia, a number of factors may influence functional decline in addition to
cognition. In this study, we aimed to study the potential association of the number of …

Clinical trajectories of neuropsychiatric symptoms in mild-moderate to advanced dementia

IM Castillo-García, J López-Álvarez… - Journal of …, 2022 - content.iospress.com
Background: There is high prevalence of neuropsychiatric symptoms (NPS) among
dementia patients. NPS are correlated with dementia progression, functional decline, early …

Towards defining the neuroanatomical basis of late-onset psychiatric symptoms

MS Barker, SA Cosentino, R Fremont… - Journal of Geriatric …, 2022 - journals.sagepub.com
Psychiatric symptoms, including changes in emotional processing, are a common feature of
many neurodegenerative disorders, such as Alzheimer's disease, dementia with Lewy …

[HTML][HTML] The impact of medication reviews by general practitioners on psychotropic drug use and behavioral and psychological symptoms in home-dwelling people …

MH Gedde, BS Husebo, J Mannseth, M Naik… - BMC medicine, 2022 - Springer
Background There is limited knowledge regarding the process of deprescribing psychotropic
drugs to people with dementia (PwD) conducted by general practitioners (GP). We …

[HTML][HTML] Assessing Nigrostriatal Dopaminergic Pathways via 123I-FP-CIT SPECT in Dementia With Lewy Bodies in a Psychiatric Patient Cohort

N Hansen, C Lange, C Timäus, J Wiltfang… - Frontiers in aging …, 2021 - frontiersin.org
Background (123)-I-2-ß-carbomethoxy-3ß-(4-iodophenyl)-N-(3-fluoropropyl) nortro-pane
single photon emission computed tomography (123I-FP-CIT SPECT) was validated to …

Muscle volume and intramuscular fat of the tongue evaluated with MRI predict malnutrition in people living with dementia: A 5-year follow-up study

MG Borda, E Bani Hassan, JH Weon… - The Journals of …, 2022 - academic.oup.com
Malnutrition is highly prevalent in older persons with dementia. Therefore, strong predictors
of malnutrition in this population are crucial to initiating early interventions. This study …