[HTML][HTML] An overview of bioinformatics tools for epitope prediction: implications on vaccine development

RE Soria-Guerra, R Nieto-Gomez… - Journal of biomedical …, 2015 - Elsevier
Exploitation of recombinant DNA and sequencing technologies has led to a new concept in
vaccination in which isolated epitopes, capable of stimulating a specific immune response …

Literature review: The vaccine supply chain

LE Duijzer, W Van Jaarsveld, R Dekker - European Journal of Operational …, 2018 - Elsevier
Vaccination is one of the most effective ways to prevent and/or control the outbreak of
infectious diseases. This medical intervention also brings about many logistical questions. In …

The impact of COVID-19 nonpharmaceutical interventions on the future dynamics of endemic infections

RE Baker, SW Park, W Yang… - Proceedings of the …, 2020 - National Acad Sciences
Nonpharmaceutical interventions (NPIs) have been employed to reduce the transmission of
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), yet these measures are …

Where to locate COVID‐19 mass vaccination facilities?

D Bertsimas, V Digalakis Jr, A Jacquillat… - Naval Research …, 2022 - Wiley Online Library
The outbreak of COVID‐19 led to a record‐breaking race to develop a vaccine. However,
the limited vaccine capacity creates another massive challenge: how to distribute vaccines …

Predictive modeling of influenza shows the promise of applied evolutionary biology

DH Morris, KM Gostic, S Pompei, T Bedford… - Trends in …, 2018 - cell.com
Seasonal influenza is controlled through vaccination campaigns. Evolution of influenza virus
antigens means that vaccines must be updated to match novel strains, and vaccine …

Optimizing vaccine allocation to combat the COVID-19 pandemic

D Bertsimas, J Ivanhoe, A Jacquillat, M Li, A Previero… - MedRxiv, 2020 - medrxiv.org
The outbreak of COVID-19 has spurred extensive research worldwide to develop a vaccine.
However, when a vaccine becomes available, limited production and distribution …

Economic and behavioral influencers of vaccination and antimicrobial use

CE Wagner, JA Prentice, CM Saad-Roy… - Frontiers in Public …, 2020 - frontiersin.org
Despite vast improvements in global vaccination coverage during the last decade, there is a
growing trend in vaccine hesitancy and/or refusal globally. This has implications for the …

Heterosubtypic T-cell immunity to influenza in humans: challenges for universal T-cell influenza vaccines

S Sridhar - Frontiers in immunology, 2016 - frontiersin.org
Influenza A virus (IAV) remains a significant global health issue causing annual epidemics,
pandemics, and sporadic human infections with highly pathogenic avian or swine influenza …

Viral vaccines and their manufacturing cell substrates: New trends and designs in modern vaccinology

AF Rodrigues, HR Soares, MR Guerreiro… - Biotechnology …, 2015 - Wiley Online Library
Vaccination is one of the most effective interventions in global health. The worldwide
vaccination programs significantly reduced the number of deaths caused by infectious …

Masking of antigenic epitopes by antibodies shapes the humoral immune response to influenza

VI Zarnitsyna, AH Ellebedy, C Davis… - … of the Royal …, 2015 - royalsocietypublishing.org
The immune responses to influenza, a virus that exhibits strain variation, show complex
dynamics where prior immunity shapes the response to the subsequent infecting strains …