Antiseizure drugs (ASDs) prevent the occurrence of seizures; there is no evidence that they
have disease-modifying properties. In the more than 160 years that orally administered …

Antiepileptic drugs (AEDs) provide satisfactory control of seizures for most patients with
epilepsy. The drugs have the remarkable ability to protect against seizures while permitting …

Epilepsy is a highly heritable disorder affecting over 50 million people worldwide, of which
about one-third are resistant to current treatments. Here we report a multi-ancestry genome …

Epilepsy is a chronic disease that affects millions of people worldwide. Antiepileptic drugs
(AEDs) are used to control seizures. Even though parts of their mechanisms of action are …

There is an increasing interest in nootropic drugs for the treatment of CNS disorders. Since
the last meta-analysis of the clinical efficacy of piracetam, more information has …

Epilepsy is a common and devastating neurological disorder. In many patients with epilepsy,
seizures are well-controlled with currently available anti-epileptic drugs (AEDs), but a …

The global introduction of 14 new antiepileptic drugs (AEDs) over the past 20 years as
adjunctive treatment in refractory epilepsy has triggered an increased interest in optimising …

Abstract Levetiracetam (Keppra®, E Keppra®) is an established second-generation anti-
epileptic drug (AED). Worldwide, levetiracetam is most commonly approved as adjunctive …

Epilepsy is a common chronic disorder that requires long-term antiepileptic drug therapy.
Approximately one half of patients fail the initial antiepileptic drug and about 35% are …

Background: Epilepsy is a chronic brain disease that is caused by various factors and
characterized by recurrent, episodic and temporary central nervous system dysfunction …