[HTML][HTML] Allergen immunotherapy: past, present and future

SR Durham, MH Shamji - Nature Reviews Immunology, 2023 - nature.com
Allergen immunotherapy is a form of therapeutic vaccination for established IgE-mediated
hypersensitivity to common allergen sources such as pollens, house dust mites and the …

The role of allergen‐specific IgE, IgG and IgA in allergic disease

MH Shamji, R Valenta, T Jardetzky, V Verhasselt… - Allergy, 2021 - Wiley Online Library
Immunoglobulin E (IgE)‐mediated allergy is the most common hypersensitivity disease
affecting more than 30% of the population. Exposure to even minute quantities of allergens …

EAACI molecular allergology user's guide 2.0

S Dramburg, C Hilger, AF Santos… - Pediatric Allergy and …, 2023 - Wiley Online Library
Since the discovery of immunoglobulin E (IgE) as a mediator of allergic diseases in 1967,
our knowledge about the immunological mechanisms of IgE‐mediated allergies has …

IgE and IgG antibodies as regulators of mast cell and basophil functions in food allergy

C Kanagaratham, YS El Ansari, OL Lewis… - Frontiers in …, 2020 - frontiersin.org
Food allergy is a major health issue, affecting the lives of 8% of US children and their
families. There is an urgent need to identify the environmental and endogenous signals that …

[HTML][HTML] Guideline on allergen immunotherapy in IgE-mediated allergic diseases: S2K guideline of the German society of allergology and clinical immunology (DGAKI) …

O Pfaar, T Ankermann, M Augustin, P Bubel… - Allergologie …, 2022 - ncbi.nlm.nih.gov
Pneumologists, Sleep and Respiratory Physicians (BdP)(Sebastian Böing), Professional
Association of German Dermatologists (BVDD)(Klaus Strömer) were taking part in the …

A broadly protective antibody that targets the flavivirus NS1 protein

N Modhiran, H Song, L Liu, C Bletchly, L Brillault… - Science, 2021 - science.org
There are no approved flaviviral therapies and the development of vaccines against
flaviruses has the potential of being undermined by antibody-dependent enhancement …

One hundred and ten years of allergen immunotherapy: a journey from empiric observation to evidence

O Pfaar, J Bousquet, SR Durham, J Kleine‐Tebbe… - Allergy, 2022 - Wiley Online Library
One hundred and ten years after Noon's first clinical report of the subcutaneous application
of allergen extracts, allergen immunotherapy (AIT) has evolved as the most important pillar …

High-affinity allergen-specific human antibodies cloned from single IgE B cell transcriptomes

D Croote, S Darmanis, KC Nadeau, SR Quake - Science, 2018 - science.org
Immunoglobulin E (IgE) antibodies protect against helminth infections but can also cause life-
threatening allergic reactions. Despite their role in human health, the cells that produce …

Past, present, and future of allergen immunotherapy vaccines

Y Dorofeeva, I Shilovskiy, I Tulaeva, M Focke‐Tejkl… - Allergy, 2021 - Wiley Online Library
Allergen‐specific immunotherapy (AIT) is an allergen‐specific form of treatment for patients
suffering from immunoglobulin E (IgE)‐associated allergy; the most common and important …

Mechanisms of allergen-specific immunotherapy: Diverse mechanisms of immune tolerance to allergens

A Głobińska, T Boonpiyathad, P Satitsuksanoa… - Annals of Allergy …, 2018 - Elsevier
Objective The aim of this review is to provide an overview of the current knowledge on the
mechanisms of allergen immunotherapy based on the recent publications and clinical trials …