The brain requires a continuous supply of energy in the form of ATP, most of which is
produced from glucose by oxidative phosphorylation in mitochondria, complemented by …

Gastrointestinal and central function are intrinsically connected by the gut microbiota, an
ecosystem that has co-evolved with the host to expand its biotransformational capabilities …

Lactate has diverse roles in the brain at the molecular and behavioral levels under
physiological and pathophysiological conditions. This study investigates whether lysine …

Alterations in energy metabolism are associated with depression. However, the role of
glycolysis in the pathogenesis of depression and the underlying molecular mechanisms …

The gut microbiota is a complex and dynamic ecosystem essential for the proper functioning
of the organism, affecting the health and disease status of the individuals. There is …

Gut-brain axis is a dynamic, complex, and bidirectional communication network between the
gut and brain. Changes in the microbiota-gut-brain axis are responsible for developing …

It has been well established in epidemiological studies and randomized controlled trials that
habitual exercise is beneficial for brain health, such as cognition and mental health …

To date there is no cure available for dementia, and the field calls for novel therapeutic
targets. A rapidly growing body of literature suggests that regular endurance training and …

The etiopathogenesis of mental disorders is not fully understood and accumulating evidence
support that clinical symptomatology cannot be assigned to a single gene mutation, but it …

Gut microbes are associated with the development of depression based on extensive
evidence. However, previous studies have led to conflicting reports on this association …