Cancer, as a long‐lasting and dramatic disease, affects almost one‐third of human beings
globally. Chemotherapeutics play an important role in cancer treatment, but multidrug …

For the last three decades, metalloenzymes such as histone deacetylases (HDACs) and
matrix metalloproteinases (MMPs) have been identified in promoting solid as well as …

Targeted drug delivery systems are commonly used to improve the therapeutic index of anti-
cancer drugs by increasing their selectivity and reducing systemic distribution and toxicity …

Parkinson's Disease (PD) is the most rapidly growing neurological disorder globally in terms
of disability and mortality. While symptomatic treatment is available for PD, there is a critical …

Cognitive dysfunction by chemotherapy compromises the quality of life in cancer patients.
Tea polyphenols are known chemopreventive agents. The present study was designed to …

Histone deacetylase (HDAC) enzymes play a key role in cell function and are implicated in
several diseases such as inflammation, cancer, and neurodegeneration. Studies on natural …

Abstract Imbalance of Treg/Th17 and chronic synovitis characterized by the recruitment and
infiltration of inflammatory cells are the typical features of rheumatoid arthritis (RA). IL-6 …

Multiple genetic mutations along with unusual epigenetic modifications play a major role in
cancer development. Histone deacetylase (HDAC) enzyme overexpression observed in the …

Considering the therapeutic values of bioflavonoids in colon cancer treatment, six 2ʹ-
hydroxy chalcones (C1-C6) were synthesized, characterized and screened for in vitro …

Background: Propolis, a resinous substance produced by the honeybee, has a wide
spectrum of potent biological activities. However, anti-cancer activity of propolis obtained …