Depression and anxiety in inflammatory bowel disease: epidemiology, mechanisms and treatment

TH Bisgaard, KH Allin, L Keefer… - Nature reviews …, 2022 - nature.com
Inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis, is a
chronic, relapsing immune-mediated disease with a varying and sometimes severe disease …

Tryptophan-kynurenine metabolism: a link between the gut and brain for depression in inflammatory bowel disease

LM Chen, CH Bao, Y Wu, SH Liang, D Wang… - Journal of …, 2021 - Springer
Inflammatory bowel disease (IBD), which mainly includes ulcerative colitis (UC) and Crohn's
disease (CD), is a group of chronic bowel diseases that are characterized by abdominal …

Controversies revisited: a systematic review of the comorbidity of depression and anxiety with inflammatory bowel diseases

A Mikocka-Walus, SR Knowles… - Inflammatory bowel …, 2016 - academic.oup.com
Background Although mental health concerns are known to occur commonly for those with
inflammatory bowel diseases (IBD), the nature of this comorbid relationship has not been …

Inflammatory bowel disease and Parkinson's disease: common pathophysiological links

HS Lee, E Lobbestael, S Vermeire, J Sabino, I Cleynen - Gut, 2021 - gut.bmj.com
Inflammatory bowel disease and Parkinson's disease are chronic progressive disorders that
mainly affect different organs: the gut and brain, respectively. Accumulating evidence has …

The influence of the brain–gut axis in inflammatory bowel disease and possible implications for treatment

DJ Gracie, PJ Hamlin, AC Ford - The lancet Gastroenterology & …, 2019 - thelancet.com
Brain–gut interactions affect psychological wellbeing and symptom reporting in functional
gastrointestinal disorders; the presence of anxiety or depression is associated with the …

Depression and anxiety in patients with active ulcerative colitis: crosstalk of gut microbiota, metabolomics and proteomics

X Yuan, B Chen, Z Duan, Z Xia, Y Ding, T Chen… - Gut …, 2021 - Taylor & Francis
Patients with ulcerative colitis (UC) have a high prevalence of mental disorders, such as
depression and anxiety. Gut microbiota imbalance and disturbed metabolism have been …

Mechanisms by which stress affects the experimental and clinical inflammatory bowel disease (IBD): role of brain-gut axis

B Brzozowski, A Mazur-Bialy, R Pajdo… - Current …, 2016 - ingentaconnect.com
Background: Stress of different origin is known to alter so called “braingut axis” and
contributes to a broad array of gastrointestinal disorders including inflammatory bowel …

Gut–brain actions underlying comorbid anxiety and depression associated with inflammatory bowel disease

Á Abautret-Daly, E Dempsey, A Parra-Blanco… - Acta …, 2018 - cambridge.org
IntroductionInflammatory bowel disease (IBD) is a chronic relapsing and remitting disorder
characterised by inflammation of the gastrointestinal tract. There is a growing consensus that …

Lycopene alleviates DSS-induced colitis and behavioral disorders via mediating microbes-gut–brain axis balance

B Zhao, J Wu, J Li, Y Bai, Y Luo, B Ji, B Xia… - Journal of agricultural …, 2020 - ACS Publications
Gut microbes play significant roles in colitis development. The current study was aimed to
uncover the preventive effects of lycopene (LYC), a functional carotenoid component, on …

[HTML][HTML] Effects of alternate-day fasting, time-restricted fasting and intermittent energy restriction DSS-induced on colitis and behavioral disorders

X Zhang, Q Zou, B Zhao, J Zhang, W Zhao, Y Li, R Liu… - Redox biology, 2020 - Elsevier
Intermittent fasting (IF) has been reported to have beneficial effects on improving gut function
via lowering gut inflammation and altering the gut microbiome diversity. In this study, we …