Insulin-sensitizing medications were originally used in psychiatric practice to treat weight
gain and other metabolic side effects that accompany the use of mood stabilizers …

Growing evidence suggests there is a bidirectional relationship between depression and
obesity, which are associated with structural and functional brain abnormalities. However …

Background: Obesity is highly prevalent and disabling, especially in individuals with severe
mental illness including bipolar disorders (BD). The brain is a target organ for both obesity …

Baek et al in this issue of the Journal present results from a longitudinal observational study
that aimed to ascertain whether a correlation exists between depressive symptom …

BackgroundIndividuals with bipolar disorder are commonly correctly diagnosed a decade
after symptom onset. Machine learning techniques may aid in early recognition and reduce …

Offspring of parents with bipolar disorder (BD offspring) with subthreshold symptoms are
particularly vulnerable to future disease onset, yet most of them remain clinically unaffected …

Multivariate techniques better fit the anatomy of complex neuropsychiatric disorders which
are characterized not by alterations in a single region, but rather by variations across …

Exposure to stress, particularly during childhood, has been linked to chronic medical
conditions, including mental disorders. In recent years, advancements in modern …

Background The St. Göran Bipolar Project (SBP) was launched as a longitudinal outpatient
study investigation. The overarching objective was to identify predictive factors associated …

Obesity is a highly prevalent metabolic risk factor that commonly coincides with additional
metabolic, cardiovascular, and inflammatory abnormalities. Obesity has frequently been …