This review article summarizes the recent advances in pathogenic mechanisms and novel
therapeutic strategies for osteomyelitis, covering both periprosthetic joint infections and …

Like any foreign object, orthopaedic implants are susceptible to infection when introduced
into the human body. Without additional preventative measures, the absolute number of …

Background: Preoperative identification of patients at risk for periprosthetic joint infection
(PJI) following total hip arthroplasty (THA) or total knee arthroplasty (TKA) is important for …

The optimal prophylactic antibiotic should be a bactericidal agent against the most common
organisms responsible for causing surgical site infections/periprosthetic joint infections …

Prosthetic joint infection (PJI) is a feared complication of total joint arthroplasty associated
with increased morbidity and mortality. There is a growing body of evidence that bacterial …

Periprosthetic joint infection (PJI) is a devastating complication seen in total joint arthroplasty
(TJA) patients. Traditionally, the serologic diagnosis of PJI was performed by measuring …

Background Periprosthetic joint infection (PJI) represents a devastating complication of total
hip arthroplasty (THA) or total knee arthroplasty (TKA). Modifiable patient risk factors as well …

Background Diagnosis and treatment of culture negative total knee arthroplasty (TKA)
periprosthetic joint infection (PJI) is challenging. There is debate over whether culture …

Results: Of 7177 potentially relevant citations, 101 studies were finally included in this
review. No RCTs relevant to the review topic were identified.

Background Risk of subsequent periprosthetic joint infection (PJI) in a second prosthetic
joint following initial PJI has been shown to be 19%-20%. We sought to identify (1) the risk of …