Impact of obesity on influenza A virus pathogenesis, immune response, and evolution
R Honce, S Schultz-Cherry - Frontiers in immunology, 2019 - frontiersin.org
With the rising prevalence of obesity has come an increasing awareness of its impact on
communicable disease. As a consequence of the 2009 H1N1 influenza A virus pandemic …
communicable disease. As a consequence of the 2009 H1N1 influenza A virus pandemic …
Innate receptor activation patterns involving TLR and NLR synergisms in COVID-19, ALI/ARDS and sepsis cytokine storms: a review and model making novel …
R Root-Bernstein - International journal of molecular sciences, 2021 - mdpi.com
Severe COVID-19 is characterized by a “cytokine storm”, the mechanism of which is not yet
understood. I propose that cytokine storms result from synergistic interactions among Toll …
understood. I propose that cytokine storms result from synergistic interactions among Toll …
The role of dysregulated immune responses in COVID-19 pathogenesis
S Tahaghoghi-Hajghorbani, P Zafari, E Masoumi… - Virus research, 2020 - Elsevier
Abstract The coronavirus disease-2019 (COVID-19) which caused by severe acute
respiratory syndrome-related coronavirus (SARS-CoV-2), is a pandemic threat to global …
respiratory syndrome-related coronavirus (SARS-CoV-2), is a pandemic threat to global …
Obesity dysregulates the pulmonary antiviral immune response
Obesity is a well-recognized risk factor for severe influenza infections but the mechanisms
underlying susceptibility are poorly understood. Here, we identify that obese individuals …
underlying susceptibility are poorly understood. Here, we identify that obese individuals …
Obesity is a strong risk factor for short-term mortality and adverse outcomes in Mexican patients with COVID-19: a national observational study
JM Vera-Zertuche, J Mancilla-Galindo… - Epidemiology & …, 2021 - cambridge.org
Conflicting results have been obtained through meta-analyses for the role of obesity as a
risk factor for adverse outcomes in patients with coronavirus disease-2019 (COVID-19) …
risk factor for adverse outcomes in patients with coronavirus disease-2019 (COVID-19) …
Dysregulated inflammation during obesity: driving disease severity in influenza virus and SARS-CoV-2 infections
Acute inflammation is a critical host defense response during viral infection. When
dysregulated, inflammation drives immunopathology and tissue damage. Excessive …
dysregulated, inflammation drives immunopathology and tissue damage. Excessive …
Immunity to influenza: impact of obesity
SA Rojas-Osornio, TR Cruz-Hernández… - Obesity Research & …, 2019 - Elsevier
Obesity is a health concern that is recognized as a critical factor for vulnerability to influenza
A/pdmH1N1 virus infection, with epidemiological and clinical impacts. In humans, obesity …
A/pdmH1N1 virus infection, with epidemiological and clinical impacts. In humans, obesity …
[HTML][HTML] Obesity and severe coronavirus disease 2019: molecular mechanisms, paths forward, and therapeutic opportunities
T Yan, R Xiao, N Wang, R Shang, G Lin - Theranostics, 2021 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appears to have higher
pathogenicity among patients with obesity. Obesity, termed as body mass index greater than …
pathogenicity among patients with obesity. Obesity, termed as body mass index greater than …
Baicalin Induces a Potent Innate Immune Response to Inhibit Respiratory Syncytial Virus Replication via Regulating Viral Non-Structural 1 and Matrix RNA
S Qin, X Huang, S Qu - Frontiers in Immunology, 2022 - frontiersin.org
Respiratory syncytial virus (RSV) infection is the most frequent cause of hospitalization in
pediatric patients. Current systemic treatment and vaccines are not curative and re-infection …
pediatric patients. Current systemic treatment and vaccines are not curative and re-infection …
Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a
R Li, L Wang - Molecular Medicine Reports, 2019 - spandidos-publications.com
Influenza virus A (IVA) is one of the predominant causative agents of the seasonal flu and
has become an important cause of morbidity worldwide. Great efforts have been paid to …
has become an important cause of morbidity worldwide. Great efforts have been paid to …