Carlos Chagas discovered American trypanosomiasis, also named Chagas disease (CD) in
his honor, just over a century ago. He described the clinical aspects of the disease …

Background: Chagas disease, resulting from the protozoan Trypanosoma cruzi, is an
important cause of heart failure, stroke, arrhythmia, and sudden death. Traditionally …

Chagas disease (CD) is a tropical neglected illness, affecting mainly populations of low
socioeconomic status in Latin America. An estimated 6 to 8 million people worldwide are …

Background Indigenous peoples are vulnerable to pandemics, including to the coronavirus
disease (COVID)-19, since it causes high mortality and specially, the loss of elderly …

Background Chagas disease (CD) remains an important endemic disease in Latin America.
However, CD became globalized in recent decades. The majority of the chronically infected …

Naphthoquinones are of key importance in organic synthesis and medicinal chemistry. In the
last few years, various synthetic routes have been developed to prepare bioactive …

Chagas disease (ChD) is a zoonotic protozoan infection caused by Trypanosoma cruzi and
naturally transmitted by domestic and sylvatic blood-sucking triatomine bugs, known as …

Chagas disease is a neglected tropical disease and a global public health issue. In terms of
treatment, no progress has been made since the 1960s, when benznidazole and nifurtimox …

A DC (tripanossomíase americana) é entidade mórbida transmissível, potencialmente fatal,
causada pelo protozoário parasita T. cruzi e que integra o grupo de doenças tropicais …

Introduction Benznidazole is the preferred drug for treatment of Chagas disease. However, it
is toxic and of limited value in chronic infection. Objective We aimed to estimate the rates of …