Mechanics of the stomach: A review of an emerging field of biomechanics

S Brandstaeter, SL Fuchs, RC Aydin… - GAMM …, 2019 - Wiley Online Library
Mathematical and computational modeling of the stomach is an emerging field of
biomechanics where several complex phenomena, such as gastric electrophysiology, fluid …

Strategies to refine gastric stimulation and pacing protocols: experimental and modeling approaches

LK Cheng, ND Nagahawatte, R Avci, P Du… - Frontiers in …, 2021 - frontiersin.org
Gastric pacing and stimulation strategies were first proposed in the 1960s to treat motility
disorders. However, there has been relatively limited clinical translation of these techniques …

Phase waves and trigger waves: emergent properties of oscillating and excitable networks in the gut

SP Parsons, JD Huizinga - The Journal of physiology, 2018 - Wiley Online Library
The gut is enmeshed by a number of cellular networks, but there is only a limited
understanding of how these networks generate the complex patterns of activity that drive gut …

In silico model of colon electromechanics for manometry prediction after laser tissue soldering

RT Djoumessi, P Lenarda, A Gizzi, S Giusti… - Computer Methods in …, 2024 - Elsevier
The present study introduces an advanced multi-physics and multi-scale modeling approach
to investigate in silico colon motility. We introduce a generalized electromechanical …

A viscoelastic framework for inflation testing of gastrointestinal tissue

SK Panda, ML Buist - Journal of the mechanical behavior of biomedical …, 2020 - Elsevier
Gastrointestinal (GI) diseases are often associated with hypertrophy of the layers of the GI
wall, along with dilatation and a denervation of smooth muscle cells which alters the …

Slow wave conduction patterns in the stomach: from W aller's Foundations to Current Challenges

LK Cheng - Acta Physiologica, 2015 - Wiley Online Library
This review provides an overview of our understanding of motility and slow wave
propagation in the stomach. It begins by reviewing seminal studies conducted by W alter C …

A finite element approach for gastrointestinal tissue mechanics

SK Panda, ML Buist - International journal for numerical …, 2019 - Wiley Online Library
The biomechanical properties of gastrointestinal (GI) tissue play a significant role in the
normal functioning of the organ. GI soft tissues exhibit a highly nonlinear rate‐and time …

Current applications of mathematical models of the interstitial cells of Cajal in the gastrointestinal tract

SA Mah, R Avci, LK Cheng, P Du - WIREs mechanisms of …, 2021 - Wiley Online Library
The interstitial cells of Cajal (ICC) form interconnected networks throughout the
gastrointestinal (GI) tract. ICC act as the pacemaker cells that initiate the rhythmic …

The origin of intraluminal pressure waves in gastrointestinal tract

S Sharma, ML Buist - Medical & Biological Engineering & Computing, 2024 - Springer
The gastrointestinal (GI) peristalsis is an involuntary wave-like contraction of the GI wall that
helps to propagate food along the tract. Many GI diseases, eg, gastroparesis, are known to …

Biomechanical Modelling of Gastrointestinal Smooth Muscle

SK Panda - 2018 - search.proquest.com
Gastrointestinal motility is the result of highly coordinated contraction and relaxation patterns
generated by smooth muscle cells to mix and transport ingested food along the GI tract. The …