Meta-analysis: exposure to early life stress and risk for depression in childhood and adolescence

J LeMoult, KL Humphreys, A Tracy… - Journal of the American …, 2020 - Elsevier
Objective Early life stress (ELS) is associated with increased risk for the development of
major depressive disorder (MDD) in adulthood; however, the degree to which ELS is …

The devastating clinical consequences of child abuse and neglect: increased disease vulnerability and poor treatment response in mood disorders

ETC Lippard, CB Nemeroff - American journal of psychiatry, 2023 - psychiatryonline.org
A large body of evidence has demonstrated that exposure to childhood maltreatment at any
stage of development can have long-lasting consequences. It is associated with a marked …

Child maltreatment and depression: A meta-analysis of studies using the Childhood Trauma Questionnaire

KL Humphreys, J LeMoult, JG Wear, HA Piersiak… - Child abuse & …, 2020 - Elsevier
Background Researchers have documented that child maltreatment is associated with
adverse long-term consequences for mental health, including increased risk for depression …

Psychological resilience: An update on definitions, a critical appraisal, and research recommendations

CA Denckla, D Cicchetti, LD Kubzansky… - European Journal of …, 2020 - Taylor & Francis
Background: The ability to resist adverse outcomes, or demonstrate resilience after
exposure to trauma is a thriving field of study. Yet ongoing debate persists regarding …

Long-term outcomes of childhood sexual abuse: an umbrella review

HP Hailes, R Yu, A Danese, S Fazel - The Lancet Psychiatry, 2019 - thelancet.com
Background Although many meta-analyses have examined the association between
childhood sexual abuse and subsequent outcomes, the scope, validity, and quality of this …

Prevalence and associated factors of antenatal depression: Systematic reviews and meta-analyses

X Yin, N Sun, N Jiang, X Xu, Y Gan, J Zhang… - Clinical psychology …, 2021 - Elsevier
To evaluate the global prevalence of antenatal depression and clarify its potential
associated factors, we conducted two systematic reviews and meta-analyses, where …

Evaluating the mental health impacts of the COVID-19 pandemic: Perceived risk of COVID-19 infection and childhood trauma predict adult depressive symptoms in …

AW Kim, T Nyengerai, E Mendenhall - Psychological medicine, 2022 - cambridge.org
BackgroundSouth Africa's national lockdown introduced serious threats to public mental
health in a society where one in three individuals develops a psychiatric disorder during …

The clinical characterization of the adult patient with depression aimed at personalization of management

M Maj, DJ Stein, G Parker, M Zimmerman… - World …, 2020 - Wiley Online Library
Depression is widely acknowledged to be a heterogeneous entity, and the need to further
characterize the individual patient who has received this diagnosis in order to personalize …

Heterogeneity in psychiatric diagnostic classification

K Allsopp, J Read, R Corcoran, P Kinderman - Psychiatry research, 2019 - Elsevier
The theory and practice of psychiatric diagnosis are central yet contentious. This paper
examines the heterogeneous nature of categories within the DSM-5, how this heterogeneity …

Epigenetics and depression

S Penner-Goeke, EB Binder - Dialogues in clinical neuroscience, 2019 - Taylor & Francis
The risk for major depression is both genetically and environmentally determined. It has
been proposed that epigenetic mechanisms could mediate the lasting increases in …