Alternatives to gadolinium-based metal chelates for magnetic resonance imaging
Magnetic resonance imaging (MRI) has been immensely valuable in diagnostic clinical
imaging over the last few decades owing to its exceptional spatial and anatomical …
imaging over the last few decades owing to its exceptional spatial and anatomical …
Lanthanide complexes with polyaminopolycarboxylates as prospective NMR/MRI diagnostic probes: peculiarities of molecular structure, dynamics and paramagnetic …
EN Zapolotsky, Y Qu, SP Babailov - Journal of Inclusion Phenomena and …, 2022 - Springer
The paramagnetic lanthanide complexes with polyaminopolycarboxylate (PAPC) ligands
attract considerable attention from the standpoint of potential applications thereof as …
attract considerable attention from the standpoint of potential applications thereof as …
In vivo chemical exchange saturation transfer imaging allows early detection of a therapeutic response in glioblastoma
K Sagiyama, T Mashimo, O Togao… - Proceedings of the …, 2014 - National Acad Sciences
Glioblastoma multiforme (GBM), which account for more than 50% of all gliomas, is among
the deadliest of all human cancers. Given the dismal prognosis of GBM, it would be …
the deadliest of all human cancers. Given the dismal prognosis of GBM, it would be …
The importance of water exchange rates in the design of responsive agents for MRI
The rate of water exchange in lanthanide complexes is often overlooked as an important
parameter in the design of responsive MR imaging agents. Most often, the number of inner …
parameter in the design of responsive MR imaging agents. Most often, the number of inner …
Comparative paraCEST effect of amide and hydroxy groups in divalent cobalt and nickel complexes of tripyridine-based ligands
Co (II) and Ni (II) complexes of two tri-pyridine-based ligands with two hydroxy and two
amide exchangeable protons (TDTA) and with six amide exchangeable protons (TMTP) …
amide exchangeable protons (TDTA) and with six amide exchangeable protons (TMTP) …
Europium (III) DOTA-tetraamide complexes as redox-active MRI sensors
SJ Ratnakar, S Viswanathan, Z Kovacs… - Journal of the …, 2012 - ACS Publications
PARACEST redox sensors containing the NAD+/NADH mimic N-methylquinolinium moiety
as a redox-active functional group have been designed and synthesized. The Eu3+ complex …
as a redox-active functional group have been designed and synthesized. The Eu3+ complex …
Salicylic acid and analogues as diaCEST MRI contrast agents with highly shifted exchangeable proton frequencies.
More than water: Chemical exchange saturation transfer (CEST) contrast agents have used
water bound to lanthanides as a source of highly shifted exchangeable proton frequencies …
water bound to lanthanides as a source of highly shifted exchangeable proton frequencies …
Redox-activated MRI contrast agents based on lanthanide and transition metal ions
PB Tsitovich, PJ Burns, AM McKay… - Journal of Inorganic …, 2014 - Elsevier
The reduction/oxidation (redox) potential of tissue is tightly regulated in order to maintain
normal physiological processes, but is disrupted in disease states. Thus, the development of …
normal physiological processes, but is disrupted in disease states. Thus, the development of …
Comparison of divalent transition metal ion paraCEST MRI contrast agents
SJ Dorazio, AO Olatunde, PB Tsitovich… - JBIC Journal of Biological …, 2014 - Springer
Transition-metal-ion-based paramagnetic chemical exchange saturation transfer
(paraCEST) agents are a promising new class of compounds for magnetic resonance …
(paraCEST) agents are a promising new class of compounds for magnetic resonance …
Water exchange in lanthanide complexes for MRI applications. Lessons learned over the last 25 years
P Caravan, D Esteban-Gómez… - Dalton …, 2019 - pubs.rsc.org
The water exchange rates of water molecules coordinated to the metal ion in lanthanide
complexes have been profusely investigated during the last 25 years, especially in the case …
complexes have been profusely investigated during the last 25 years, especially in the case …