Immunotherapeutic nanoparticles (NPs) could be a viable option for delivering cytotoxic
agents in a manner which suppresses their toxic manifestations. Doxorubicin (DOX) loaded …

A conjugate of the antitumor drug, methotrexate (MTX), with a diblock methoxypoly (ethylene
glycol)–poly (caprolactone)(mPEG–PCL) copolymer was synthesized by the reaction of the …

Methotrexate is one of the most effective drugs that is commonly used in the treatment of
cancer. However, its application is limited due to low solubility, high toxicity and rapid …

Polymer micelles have emerged as promising carriers for controlled release applications,
however, several limitations of micelle-based drug delivery have also been reported. To …

Blockpolymer micelles having acrylated end groups were fabricated for the development of
mucoadhesive drug loaded vehicle. The critical micelle concentration (CMC) of Pluronic® …

Background: Pazopanib hydrochloride (PZB) is a protein kinase inhibitor approved by the
United States Food and Drug Administration and European agencies for the treatment of …

Multidrug resistance (MDR) is the major cause of tumor chemotherapy failure. This study
aimed to combine doxorubicin with the MDR-reversal agent psoralen (PSO) by loading them …