SGLT2 inhibition via empagliflozin improves endothelial function and reduces mitochondrial oxidative stress: insights from frail hypertensive and diabetic patients
P Mone, F Varzideh, SS Jankauskas, A Pansini… - …, 2022 - Am Heart Assoc
Background: Frailty is a multidimensional condition often diagnosed in older adults with
hypertension and diabetes, and both these conditions are associated with endothelial …
hypertension and diabetes, and both these conditions are associated with endothelial …
The outcome of frailty in older people with diabetes as a function of glycaemic control and hypoglycaemic therapy: a review
GL Keegan, N Bhardwaj… - Expert Review of …, 2023 - Taylor & Francis
Introduction Frailty is an emerging and newly recognized complication of diabetes in older
people. However, frailty is not thoroughly investigated in diabetes outcome studies. Areas …
people. However, frailty is not thoroughly investigated in diabetes outcome studies. Areas …
Cysteine and methionine oxidation in thrombotic disorders
Thrombosis is the leading cause of death in many diseased conditions. Oxidative stress is
characteristic of these conditions. Yet, the mechanisms through which oxidants become …
characteristic of these conditions. Yet, the mechanisms through which oxidants become …
Potential Therapeutic Properties of the Leaf of Cydonia Oblonga Mill. Based on Mineral and Organic Profiles
DM Ferreira, NM de Oliveira, L Lopes, J Machado… - Plants, 2022 - mdpi.com
Leaf extract of Cydonia Oblonga Mill. is interesting for further exploration of the potential of
its substrates for therapeutic supplements. Quantitative and qualitative analyses were …
its substrates for therapeutic supplements. Quantitative and qualitative analyses were …
[HTML][HTML] Endothelial-dependent S-Sulfhydration of tissue factor pathway inhibitor regulates blood coagulation
J Wittig, MK Drekolia, A Kyselova, FD Lagos… - Redox biology, 2023 - Elsevier
Tissue factor pathway inhibitor (TFPI) is an important regulator of coagulation and a link
between inflammation and thrombosis. Here we investigated whether endothelial cell-driven …
between inflammation and thrombosis. Here we investigated whether endothelial cell-driven …
Analysis of thrombosis formation and growth using microfluidic chips and multiphase computational fluid dynamics
Thrombosis is a vascular disease associated with severe risks such as heart attack and
stroke. Extensive research has been conducted worldwide to identify the underlying causes …
stroke. Extensive research has been conducted worldwide to identify the underlying causes …
Redox mechanisms of platelet activation in aging
SX Gu, S Dayal - Antioxidants, 2022 - mdpi.com
Aging is intrinsically linked with physiologic decline and is a major risk factor for a broad
range of diseases. The deleterious effects of advancing age on the vascular system are …
range of diseases. The deleterious effects of advancing age on the vascular system are …
Risk factors for arterial catheter failure and complications during critical care hospitalisation: a secondary analysis of a multisite, randomised trial
Abstract Objectives Arterial catheters (ACs) are critical for haemodynamic monitoring and
blood sampling but are prone to complications. We investigated the incidence and risk …
blood sampling but are prone to complications. We investigated the incidence and risk …
Targeting Cysteine Oxidation in Thrombotic Disorders
M Yang, RL Silverstein - Antioxidants, 2024 - mdpi.com
Oxidative stress increases the risk for clinically significant thrombotic events, yet the
mechanisms by which oxidants become prothrombotic are unclear. In this review, we …
mechanisms by which oxidants become prothrombotic are unclear. In this review, we …
Influence of diabetes on the risk of deep vein thrombosis of patients after total knee arthroplasty: a meta-analysis
J An, L Han, X Ma, Y Chang, C Zhang - Journal of Orthopaedic Surgery …, 2024 - Springer
Background Previous studies evaluating the influence of diabetes on the risk of deep vein
thrombosis (DVT) after total knee arthroplasty (TKA) showed inconsistent results. The aim of …
thrombosis (DVT) after total knee arthroplasty (TKA) showed inconsistent results. The aim of …