[HTML][HTML] The regulations of telomerase reverse transcriptase (TERT) in cancer
M Liu, Y Zhang, Y Jian, L Gu, D Zhang, H Zhou… - Cell Death & …, 2024 - nature.com
Abnormal activation of telomerase occurs in most cancer types, which facilitates escaping
from cell senescence. As the key component of telomerase, telomerase reverse …
from cell senescence. As the key component of telomerase, telomerase reverse …
[HTML][HTML] Clinical Implications of Helicobacter pylori Antibiotic Resistance in Italy: A Review of the Literature
EC Nista, A Pellegrino, L Giuli, M Candelli, T Schepis… - Antibiotics, 2022 - mdpi.com
Helicobacter pylori (H. pylori) resistance to antibiotics has increased worldwide in recent
decades, especially to clarithromycin. As a result, the World Health Organization (WHO) …
decades, especially to clarithromycin. As a result, the World Health Organization (WHO) …
G-quadruplex motifs in Neisseria gonorrhoeae as anti-gonococcal targets
Neisseria gonorrhoeae is an obligate human pathogen that causes gonorrhea and has
shown a vast emergence of multidrug resistance in recent times. It is necessary to develop …
shown a vast emergence of multidrug resistance in recent times. It is necessary to develop …
[HTML][HTML] Gut microbiome and serum amino acid metabolome alterations in autism spectrum disorder
X Chang, Y Zhang, X Chen, S Li, H Mei, H Xiao… - Scientific Reports, 2024 - nature.com
Gut microbiota and their metabolic products might play important roles in regulating the
pathogenesis of autism spectrum disorder (ASD). The purpose of this study was to …
pathogenesis of autism spectrum disorder (ASD). The purpose of this study was to …
Telomere-related DNA damage response pathways in cancer therapy: prospective targets
L Gu, M Liu, Y Zhang, H Zhou, Y Wang… - Frontiers in …, 2024 - frontiersin.org
Maintaining the structural integrity of genomic chromosomal DNA is an essential role of
cellular life and requires two important biological mechanisms: the DNA damage response …
cellular life and requires two important biological mechanisms: the DNA damage response …
Characterization of G-quadruplex structures in genes involved in survival and pathogenesis of Acinetobacter baumannii as a potential drug target
Acinetobacter baumannii is a notorious pathogen that commonly thrives in hospital
environments and is responsible for numerous nosocomial infections in humans. The …
environments and is responsible for numerous nosocomial infections in humans. The …
The Rise of Bacterial G-Quadruplexes in Current Antimicrobial Discovery
Antimicrobial resistance (AMR) is a silent critical issue that poses several challenges to
health systems. While the discovery of novel antibiotics is currently stalled and prevalently …
health systems. While the discovery of novel antibiotics is currently stalled and prevalently …
Characterization of G‐quadruplexes in the Helicobacter pylori genome and assessment of therapeutic potential of G4 ligands
Helicobacter pylori, a leading human pathogen associated with duodenal ulcer and gastric
cancer, presents a significant threat to human health due to increasing antibiotic resistance …
cancer, presents a significant threat to human health due to increasing antibiotic resistance …
DNA Structural Elements as Potential Targets for Regulation of Gene Expression
M Palumbo, C Sissi - Handbook of Chemical Biology of Nucleic Acids, 2023 - Springer
Regulation of gene expression is one of the fundamental functions of a living organism. It is
not sufficient to make a desired cell component through specific mechanism (s), since the …
not sufficient to make a desired cell component through specific mechanism (s), since the …