The role of titanium dioxide (E171) and the requirements for replacement materials in oral solid dosage forms: An IQ Consortium Working Group Review

R Blundell, P Butterworth, A Charlier, D Daurio… - Journal of …, 2022 - Elsevier
Titanium dioxide (in the form of E171) is a ubiquitous excipient in tablets and capsules for
oral use. In the coating of a tablet or in the shell of a capsule the material disperses visible …

Univariate and multivariate determination of dapagliflozin and saxagliptin in bulk and dosage form

MM Elhassan, AM Mahmoud… - Journal of AOAC …, 2023 - academic.oup.com
Background Dapagliflozin is a sodium glucose cotransporter-II inhibitor while saxagliptin is a
dipeptidyl peptidase-4 inhibitor. Both are used to manage type 2 diabetes mellitus. Objective …

A new strategy for the determination of the antidiabetics alogliptin, saxagliptin and vildagliptin using all-solid state potentiometric sensors

AR Derar, N Ahmed, EM Hussien - BMC chemistry, 2023 - Springer
Herein, we report on the development of disposable screen printed carbon, nanostructure
thin film Au/Pt and Pt/Pt all-solid state potentiometric sensors for some antidiabetic …

Different approaches for the assessment of greenness of spectrophotometric methodologies utilized for resolving the spectral overlap of newly approved binary …

MG Fawzy, WE Hassan, AA Mostafa… - Spectrochimica Acta Part A …, 2022 - Elsevier
Simultaneous measurement of saxagliptin hydrochloride (SAG) and dapagliflozin
propanediol monohydrate (DAG) in bulk powder, laboratory-prepared mixtures, and …

Novel univariate spectrophotometric determination of the recently released solid dosage form comprising dapagliflozin and saxagliptin via factorized response spectra …

HM Lotfy, D Mohamed, MS Elshahed - Spectrochimica Acta Part A …, 2019 - Elsevier
Dapagliflozin (DPF) and saxagliptin (SXG) are currently co-formulated in a tablet dosage
form which is prescribed to improve glycemic control. The absorption spectra of DPF and …

[PDF][PDF] Simple quantified and validated stability indicating stress degradation studies of oral anti-diabetic agent dapagliflozin by RP-HPLC method

A Murugesan, MM Annapurna - Int J Appl Pharmaceut, 2022 - academia.edu
Objective: This method is focused on developing a precisely simplified and more accurate
Reverse Phase–High Pressure Liquid Chromatography (RP-HPLC) method for the …

Development and validation of RP-HPLC method for simultaneous estimation of saxagliptin and dapagliflozin in tablets

SS More, SS Sonawane, SS Chhajed… - Asian Journal of …, 2018 - indianjournals.com
A simple, accurate, precise and selective RP-HPLC method was developed and validated
for simultaneous estimation of Saxagliptin (SAXA) and Dapagliflozin (DAPA) in tablet …

Fabrication, optimization, and eco-friendly micellar HPLC determination of Alogliptin/Dapagliflozin pullulan-based sublingual films for therapeutic efficacy …

MKA Khalifa, AM Dawaba, HM Dawaba… - Journal of Drug Delivery …, 2023 - Elsevier
The aim of this study was to prepare and statistically optimize a pullulan-based sublingual
film containing Alogliptin/Dapagliflozin (ALO/DAPA) mixture, by solvent casting technique to …

Multivariate optimization of liquid chromatographic conditions for determination of dapagliflozin and saxagliptin, application to an in vitro dissolution and stability …

S Gurrala, S Raj, CVS Subrahmanyam… - Future Journal of …, 2021 - Springer
Background Analytical quality by design driven HPLC method has been optimized for
simultaneous estimation of dapagliflozin and saxagliptin in pharmaceutical dosage form …

New spectrofluorimetric analysis of dapagliflozin after derivatization with NBD‐Cl in human plasma using factorial design experiments

MA Omar, HM Ahmed, MA Abdel Hamid… - …, 2019 - Wiley Online Library
A new validated spectrofluorimetric method was proposed for dapagliflozin (DGF) analysis
in bulk, plexin its commercially available tablets and in spiked human plasma. The proposed …