Hybrid small-molecule/protein fluorescent probes are powerful tools for visualizing protein
localization and function in living cells. These hybrid probes are constructed by diverse site …

Conspectus Fluorescent labels and biosensors play central roles in biological and medical
research. Targeted to specific biomolecules or cells, they allow noninvasive imaging of the …

The versatile functions of fluorescent proteins (FPs) as fluorescence biomarkers depend on
their intrinsic chromophores interacting with the protein environment. Besides X-ray …

Our ability to observe biochemical events with high spatial and temporal resolution is
essential for understanding the functioning of living systems. Intrinsically fluorescent proteins …

In this paper, we propose a fluorescence-lifetime imaging microscopy (FLIM) multiplexing
system based on the fluorogen-activating protein FAST. This genetically encoded …

Fluorescent tools such as green fluorescent protein (GFP) have been used extensively as
reporters in biochemistry and microbiology, but GFP and other conventional fluorescent …

Using benzylidene imidazolone core, we created a panel of color‐shifted fluorogenic
ligands for FAST protein without compromise to the binding efficiency and the utility for live …

One of the essential characteristics of any tag used in bioscience and medical applications
is its size. The larger the label, the more it may affect the studied object, and the more it may …

Long-wavelength fluorescent proteins (LWFPs) and LWFP-based sensors are indispensable
tools for bioimaging and biosensing applications. However, it remains challenging to …

In this paper, we present a new series of arylidene-imidazolones with a structural motif of
Green Fluorescent Protein chromophore with a pronounced solvent-dependent FQY …