Post-activation potentiation (PAP) is a well-described phenomenon with a short half-life (~
28 s) that enhances muscle force production at submaximal levels of calcium saturation (ie …

The capacity for human exercise performance can be enhanced with prolonged exercise
training, whether it is endurance-or strength-based. The ability to adapt through exercise …

The thin and thick filaments of muscle sarcomeres are interconnected by the giant protein
titin, which is a scaffolding filament, signaling platform, and provider of passive tension and …

Titin is a filamentous protein spanning the half-sarcomere, with spring-like properties in the I-
band region. Various structural, signaling, and mechanical functions have been associated …

Over the last 20 years a number of studies have been published using progressive eccentric
exercise protocols on motorized ergometers or similar devices that allow for controlled …

Titin has long been recognized as a mechanical protein in muscle cells that has a main
function as a molecular spring in the contractile units, the sarcomeres. Recent work suggests …

The following papers by Richard Lieber (Skeletal Muscle as an Actuator), Thomas Roberts
(Elastic Mechanisms and Muscle Function), Silvia Blemker (Skeletal Muscle has a Mind of its …

When active muscles are stretched, our understanding of muscle function is stretched as
well. Our understanding of the molecular mechanisms of concentric contraction has …

This review will provide a comprehensive, up-to-date review of the current knowledge
regarding the pathophysiology of muscle contractures in cerebral palsy. Although much has …

It is well acknowledged that muscles that are elongated while activated (ie, eccentric muscle
action) are stronger and require less energy (per unit of force) than muscles that are …