THE purpose of this review is to evaluate recent developments in our understanding of the
inflammatory response to cardiac surgery. Scientific knowledge in this field is continually …

The complement cascade is a key component of the innate immune system that is rapidly
recruited through a cascade of enzymatic reactions to enable the recognition and clearance …

Objective: To test whether perioperative sodium bicarbonate infusion can attenuate
postoperative increases in serum creatinine in cardiac surgical patients. Design: Double …

Much controversy persists regarding the optimal techniques for myocardial protection during
heart surgery. Numerous studies have compared warm cardioplegia with cold cardioplegia …

THE SYSTEMIC INFLAMMATORY RESPONSE (man-ifested by pyrexia, leukocytosis,
tachycardia, hypotension, tissue fluid accumulation, and organ failure) is generated during …

Cardiopulmonary bypass is associated with significant morbidities, and the ideal
temperature management during cardiopulmonary bypass remains uncertain. This review …

Myocardial protection has become an essential adjunctive measure in cardiac surgery for a
couple of decades, because since the 1950s, the methods of cardioprotection (cardioplegic …

Objectives: The inflammatory response to cardiopulmonary bypass is believed to play an
important role in end organ dysfunction after open heart surgery and may be more profound …

Cardiac surgery with cardiopulmonary bypass (CPB) is known to induce an immune
response whose nature has been increasingly elucidated during the recent decade …

Prolonged mechanical ventilation increases hospitalization costs, airway and lung trauma,
and stress. The objective of this study was to elucidate patient characteristics and operative …