Rationale for a multi-factorial approach for the reversal of cognitive decline in Alzheimer's disease and MCI: a review

RV Rao, KG Subramaniam, J Gregory… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a multifactorial, progressive, neurodegenerative disease
typically characterized by memory loss, personality changes, and a decline in overall …

Type I Diabetes Pathoetiology and Pathophysiology: Roles of the Gut Microbiome, Pancreatic Cellular Interactions, and the 'Bystander' Activation of Memory CD8+ T …

G Anderson - International Journal of Molecular Sciences, 2023 - mdpi.com
Type 1 diabetes mellitus (T1DM) arises from the failure of pancreatic β-cells to produce
adequate insulin, usually as a consequence of extensive pancreatic β-cell destruction …

The dual angiogenesis effects via Nrf2/HO-1 signaling pathway of melatonin nanocomposite scaffold on promoting diabetic bone defect repair

T Chen, Z Wu, Q Hou, Y Mei, K Yang, J Xu… - International Journal of …, 2024 - Taylor & Francis
Purpose Given the escalating prevalence of diabetes, the demand for specific bone graft
materials is increasing, owing to the greater tendency towards bone defects and more …

Benefits of the neurogenic potential of melatonin for treating neurological and neuropsychiatric disorders

Y Potes, C Cachán-Vega, E Antuña… - International Journal of …, 2023 - mdpi.com
There are several neurological diseases under which processes related to adult brain
neurogenesis, such cell proliferation, neural differentiation and neuronal maturation, are …

The role of circadian clock-controlled mitochondrial dynamics in diabetic cardiomyopathy

Z Jin, Y Ji, W Su, L Zhou, X Wu, L Gao, J Guo… - Frontiers in …, 2023 - frontiersin.org
Diabetes mellitus is a metabolic disease with a high prevalence worldwide, and
cardiovascular complications are the leading cause of mortality in patients with diabetes …

Melatonin protects HT-22 cells against palmitic acid-induced glucolipid metabolic dysfunction and cell injuries: Involved in the regulation of synaptic plasticity and …

X Gao, H Sun, S Hao, H Sun, J Ge - Biochemical Pharmacology, 2023 - Elsevier
Melatonin (MLT) is a hormonal substance reported with various pharmacological activities.
Based on its effects of neuroprotection and metabolic regulation, the aim of the present study …

The nutritional function of active polysaccharides from marine animals: A review

X Guan, F Wang, B Zhou, X Sang, Q Zhao - Food Bioscience, 2024 - Elsevier
Marine animal polysaccharides represent some of the most crucial and effective active
compounds found within these creatures. They have garnered significant attention due to …

Melatonin attenuates cellular senescence and apoptosis in diabetic nephropathy by regulating STAT3 phosphorylation

X Fang, W Huang, Q Sun, Y Zhao, R Sun, F Liu… - Life Sciences, 2023 - Elsevier
Aims Melatonin is an endogenous hormone related to the regulation of biorhythm. Previous
researchers have found that melatonin can ameliorate diabetic nephropathy (DN), but the …

The potential of therapeutic strategies targeting mitochondrial biogenesis for the treatment of insulin resistance and type 2 diabetes mellitus

W Ding, X Yang, K Lai, Y Jiang, Y Liu - Archives of Pharmacal Research, 2024 - Springer
Type 2 diabetes mellitus (T2DM) is a persistent metabolic disorder marked by deficiencies in
insulin secretion and/or function, affecting various tissues and organs and leading to …

The underlying roles and neurobiological mechanisms of Music-Based Intervention in Alzheimer's disease: A comprehensive review

L Sun, Q Wang, J Ai - Ageing Research Reviews, 2024 - Elsevier
Non-pharmacological therapy has gained popularity in the intervention of Alzheimer's
disease (AD) due to its apparent therapeutic effectiveness and the limitation of biological …