Glaucoma in adults—screening, diagnosis, and management: a review

JD Stein, AP Khawaja, JS Weizer - Jama, 2021 - jamanetwork.com
Importance Glaucoma is the most common cause of irreversible blindness worldwide. Many
patients with glaucoma are asymptomatic early in the disease course. Primary care …

Digital technology, tele-medicine and artificial intelligence in ophthalmology: A global perspective

JPO Li, H Liu, DSJ Ting, S Jeon, RVP Chan… - Progress in retinal and …, 2021 - Elsevier
The simultaneous maturation of multiple digital and telecommunications technologies in
2020 has created an unprecedented opportunity for ophthalmology to adapt to new models …

[PDF][PDF] The lymphatic vasculature in the 21st century: novel functional roles in homeostasis and disease

G Oliver, J Kipnis, GJ Randolph, NL Harvey - Cell, 2020 - cell.com
Mammals have two specialized vascular circulatory systems: the blood vasculature and the
lymphatic vasculature. The lymphatic vasculature is a unidirectional conduit that returns …

Inflammation in Glaucoma: From the back to the front of the eye, and beyond

C Baudouin, M Kolko, S Melik-Parsadaniantz… - Progress in retinal and …, 2021 - Elsevier
The pathophysiology of glaucoma is complex, multifactorial and not completely understood.
Elevated intraocular pressure (IOP) and/or impaired retinal blood flow may cause initial optic …

Therapeutic potential of cannabis, cannabidiol, and cannabinoid-based pharmaceuticals

CA Legare, WM Raup-Konsavage, KE Vrana - Pharmacology, 2022 - karger.com
Background: There is a growing interest in the use of cannabis (and its extracts), as well as
CBD oil (hemp extracts containing cannabidiol), for therapeutic purposes. While there is …

Cellular senescence: aging, cancer, and injury

A Calcinotto, J Kohli, E Zagato… - Physiological …, 2019 - journals.physiology.org
Cellular senescence is a permanent state of cell cycle arrest that occurs in proliferating cells
subjected to different stresses. Senescence is, therefore, a cellular defense mechanism that …

[HTML][HTML] The diagnosis and treatment of glaucoma

AK Schuster, C Erb, EM Hoffmann… - Deutsches Ärzteblatt …, 2020 - ncbi.nlm.nih.gov
Background Glaucoma is a group of chronically progressive disorders of the optic nerve. In
this article, we present the epidemiology of and risk factors for glaucoma, as well as the …

[HTML][HTML] Considerations for polymers used in ocular drug delivery

MM Allyn, RH Luo, EB Hellwarth… - Frontiers in …, 2022 - frontiersin.org
Purpose: Age-related eye diseases are becoming more prevalent. A notable increase has
been seen in the most common causes including glaucoma, age-related macular …

Effectiveness of early lens extraction for the treatment of primary angle-closure glaucoma (EAGLE): a randomised controlled trial

A Azuara-Blanco, J Burr, C Ramsay, D Cooper… - The Lancet, 2016 - thelancet.com
Background Primary angle-closure glaucoma is a leading cause of irreversible blindness
worldwide. In early-stage disease, intraocular pressure is raised without visual loss …

[HTML][HTML] Immune responses to injury and their links to eye disease

MANN Stepp, ASUE Menko - Translational Research, 2021 - Elsevier
The eye is regarded as an immune privileged site. Since the presence of a vasculature
would impair vision, the vasculature of the eye is located outside of the central light path. As …