Epigenetic modifications in stress response genes associated with childhood trauma
Adverse childhood experiences (ACEs) may be referred to by other terms (eg, early life
adversity or stress and childhood trauma) and have a lifelong impact on mental and physical …
adversity or stress and childhood trauma) and have a lifelong impact on mental and physical …
The role of regulatory variation in complex traits and disease
FW Albert, L Kruglyak - Nature Reviews Genetics, 2015 - nature.com
We are in a phase of unprecedented progress in identifying genetic loci that cause variation
in traits ranging from growth and fitness in simple organisms to disease in humans …
in traits ranging from growth and fitness in simple organisms to disease in humans …
GraphR: Accelerating graph processing using ReRAM
Graph processing recently received intensive interests in light of a wide range of needs to
understand relationships. It is well-known for the poor locality and high memory bandwidth …
understand relationships. It is well-known for the poor locality and high memory bandwidth …
Defining the consequences of genetic variation on a proteome-wide scale
Genetic variation modulates protein expression through both transcriptional and post-
transcriptional mechanisms. To characterize the consequences of natural genetic diversity …
transcriptional mechanisms. To characterize the consequences of natural genetic diversity …
[图书][B] Behavioral genetics
R Plomin - 2008 - books.google.com
Behavioral Genetics, Fifth Edition provides an engaging and clear overview of human and
animal behavioral genetics that is designed to introduce students in the behavioral …
animal behavioral genetics that is designed to introduce students in the behavioral …
Multiple-trait genomic selection methods increase genetic value prediction accuracy
Y Jia, JL Jannink - Genetics, 2012 - academic.oup.com
Genetic correlations between quantitative traits measured in many breeding programs are
pervasive. These correlations indicate that measurements of one trait carry information on …
pervasive. These correlations indicate that measurements of one trait carry information on …
Relative impact of nucleotide and copy number variation on gene expression phenotypes
Extensive studies are currently being performed to associate disease susceptibility with one
form of genetic variation, namely, single-nucleotide polymorphisms (SNPs). In recent years …
form of genetic variation, namely, single-nucleotide polymorphisms (SNPs). In recent years …
Genetics of gene expression and its effect on disease
V Emilsson, G Thorleifsson, B Zhang, AS Leonardson… - Nature, 2008 - nature.com
Common human diseases result from the interplay of many genes and environmental
factors. Therefore, a more integrative biology approach is needed to unravel the complexity …
factors. Therefore, a more integrative biology approach is needed to unravel the complexity …
Autism‐like behavioral phenotypes in BTBR T+ tf/J mice
HG McFarlane, GK Kusek, M Yang… - Genes, Brain and …, 2008 - Wiley Online Library
Autism is a behaviorally defined neurodevelopmental disorder of unknown etiology. Mouse
models with face validity to the core symptoms offer an experimental approach to test …
models with face validity to the core symptoms offer an experimental approach to test …
An integrative genomics approach to infer causal associations between gene expression and disease
A key goal of biomedical research is to elucidate the complex network of gene interactions
underlying complex traits such as common human diseases. Here we detail a multistep …
underlying complex traits such as common human diseases. Here we detail a multistep …