Tendon injuries are common and present a clinical challenge to orthopedic surgery mainly
because these injuries often respond poorly to treatment and require prolonged …

This review explores state-of-the-art and new perspectives description of scaffold-based
strategies utilized in in-suit bone tissue engineering. The bone defects caused by severe …

As dense connective tissues connecting bone to muscle and bone to bone, respectively,
tendon and ligament (T/L) arise from the somitic mesoderm, originating in a recently …

Here, we fabricated thermosensitive injectable hydrogel containing poly (N-
isopropylacrylamide)(PNIPAAm)-based copolymer/graphene oxide (GO) composite with …

Periodontitis is a globally prevalent inflammatory disease that causes the destruction of the
tooth-supporting apparatus and potentially leads to tooth loss. Currently, the methods to …

Stem cell-based therapy has been one of the best documented approaches in regenerative
medicine, promising cures for a multitude of diseases and disorders. However, the ex vivo …

Injuries to the musculoskeletal system are common, debilitating and expensive. In many
cases, healing is imperfect, which leads to chronic impairment. Gene transfer might improve …

Abstract Platelet-rich plasma (PRP), a platelet concentrate made of autogenous blood, has
been used to improve bone and soft tissue defect healing in recent years. The aim of this …

The development of biological methods over the past decade has stimulated great interest in
the possibility to regenerate human tissues. Advances in stem cell research, gene therapy …

Tissue engineering uses cells, signaling molecules, and/or biomaterials to regenerate
injured or diseased tissues. Ex vivo expanded mesenchymal stem cells (MSC) have long …