The rising number of immigrants to the United States and other western countries has been
accompanied by rising interest in the characteristics of immigrants including their mortality …

Chronic, systemic inflammation is an independent risk factor for several major clinical
diseases. In obesity, circulating levels of inflammatory markers are elevated, possibly due to …

Background Because chronic obstructive pulmonary disease (COPD) is a heterogeneous
condition, the identification of specific clinical phenotypes is key to developing more effective …

Rationale: The vicious cycle hypothesis of bronchiectasis argues that bacterial colonization
leads to airway inflammation and progressive lung damage. The logical extension of this …

The incidence and diversity of chronic inflammatory diseases is increasing worldwide.
However, the complexity of clinical symptoms has made it difficult to develop therapies that …

Background—Main pulmonary artery diameter (mPA) and ratio of mPA to ascending aorta
diameter (ratio PA) derived from chest CT are commonly reported in clinical practice. We …

Background Elevated circulating levels of several inflammatory biomarkers have been
described in selected patient populations with COPD, although less is known about their …

Review highlights the function of the cytokine receptor gp130, specifically the diverse roles it
plays in inflammation, autoimmunity, and cancer. Glycoprotein 130 (gp130) is a shared …

Background Chronic obstructive pulmonary disease (COPD) is a multicomponent condition
that is characterised by airflow obstruction that is not fully reversible and is a major global …

The role of vitamin D (VitD) in calcium and bone homeostasis is well described. In the last
years, it has been recognized that in addition to this classical function, VitD modulates a …